George S. Portugal

Affiliations: 
Anesthesiology Columbia University, New York, NY 
Area:
Neurobiology of learning and memory, nicotine addiction
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"George Portugal"
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Jose A. Moron-Concepcion grad student 2010- Columbia
Matthew S. Matell grad student 2003-2005 Temple University
Thomas J. Gould grad student 2005-2010 Temple University
 (Strain-dependent and age-dependent effects of acute nicotine, chronic nicotine, and withdrawal from chronic nicotine on fear conditioning.)
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Publications

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Portugal GS, Al-Hasani R, Fakira AK, et al. (2014) Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 527-38
Fakira AK, Portugal GS, Carusillo B, et al. (2014) Increased small conductance calcium-activated potassium type 2 channel-mediated negative feedback on N-methyl-D-aspartate receptors impairs synaptic plasticity following context-dependent sensitization to morphine. Biological Psychiatry. 75: 105-14
Portugal GS, Wilkinson DS, Turner JR, et al. (2012) Developmental effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning. Neurobiology of Learning and Memory. 97: 482-94
Gould TJ, Portugal GS, André JM, et al. (2012) The duration of nicotine withdrawal-associated deficits in contextual fear conditioning parallels changes in hippocampal high affinity nicotinic acetylcholine receptor upregulation. Neuropharmacology. 62: 2118-25
Portugal GS, Wilkinson DS, Kenney JW, et al. (2012) Strain-dependent effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning. Behavior Genetics. 42: 133-50
Xia Y, Portugal GS, Fakira AK, et al. (2011) Hippocampal GluA1-containing AMPA receptors mediate context-dependent sensitization to morphine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16279-91
Portugal GS, Wilson AG, Matell MS. (2011) Behavioral sensitivity of temporally modulated striatal neurons. Frontiers in Integrative Neuroscience. 5: 30
Zhuo JM, Portugal GS, Kruger WD, et al. (2010) Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease. Current Alzheimer Research. 7: 140-9
Kenney JW, Florian C, Portugal GS, et al. (2010) Involvement of hippocampal jun-N terminal kinase pathway in the enhancement of learning and memory by nicotine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 483-92
Portugal GS, Gould TJ. (2009) Nicotine withdrawal disrupts new contextual learning. Pharmacology, Biochemistry, and Behavior. 92: 117-23
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