Jeffrey Hildebrand
Affiliations: | University of Pittsburgh, Pittsburgh, PA, United States |
Area:
Cell Biology, Molecular Biology, Anatomy BiologyGoogle:
"Jeffrey Hildebrand"Parents
Sign in to add mentor| Philippe Soriano | post-doc | 1997-2001 | Fred Hutchinson Cancer Center (DevTree) |
Children
Sign in to add trainee| Matthew J. Farber | grad student | 2011 | University of Pittsburgh |
| Debamitra Das | grad student | 2014 | University of Pittsburgh |
| Erica M. McGreevy | grad student | 2014 | University of Pittsburgh |
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Publications
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| Hildebrand JD, Leventry AD, Aideyman OP, et al. (2021) A modifier screen identifies regulators of cytoskeletal architecture as mediators of Shroom-dependent changes in tissue morphology. Biology Open. 10 |
| Zapata J, Moretto E, Hannan S, et al. (2017) Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission. Nature Communications. 8: 14536 |
| Odenwald MA, Choi W, Buckley A, et al. (2016) ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture. Journal of Cell Science |
| Zalewski JK, Mo JH, Heber S, et al. (2016) Structure of the Shroom-Rho kinase complex reveals a binding interface with monomeric Shroom that regulates cell morphology and stimulates kinase activity. The Journal of Biological Chemistry |
| Grego-Bessa J, Hildebrand J, Anderson KV. (2015) Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development (Cambridge, England). 142: 1305-14 |
| McGreevy EM, Vijayraghavan D, Davidson LA, et al. (2015) Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure. Biology Open. 4: 186-96 |
| Das D, Zalewski JK, Mohan S, et al. (2014) The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice. Biology Open. 3: 850-60 |
| Lang RA, Herman K, Reynolds AB, et al. (2014) p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis. Development (Cambridge, England). 141: 3177-87 |
| Mohan S, Das D, Bauer RJ, et al. (2013) Structure of a highly conserved domain of Rock1 required for Shroom-mediated regulation of cell morphology. Plos One. 8: e81075 |
| Mohan S, Rizaldy R, Das D, et al. (2012) Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction. Molecular Biology of the Cell. 23: 2131-42 |