Gary C. Pien, Ph.D.
Affiliations: | 2002 | Brown University, Providence, RI |
Area:
Immunology, Microbiology BiologyGoogle:
"Gary Pien"Parents
Sign in to add mentor| Christine A. Biron | grad student | 2002 | Brown | |
| (Regulation of innate and adaptive IFN-gamma responses by IL-18, IL -12, and IFN-alpha/beta.) | ||||
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Publications
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| Hui DJ, Edmonson SC, Podsakoff GM, et al. (2015) AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes. Molecular Therapy. Methods & Clinical Development. 2: 15029 |
| Hui DJ, Basner-Tschakarjan E, Chen Y, et al. (2013) Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1727-37 |
| Finn JD, Hui D, Downey HD, et al. (2010) Proteasome inhibitors decrease AAV2 capsid derived peptide epitope presentation on MHC class I following transduction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 135-42 |
| Hui DJ, Basner-Tschakarjan E, Pien GC, et al. (2010) Peptide-Induced Antigen-Specific CD4+CD25+FoxP3+ T Cells Suppress Cytotoxicity T Cell Responses Directed Against the AAV Capsid. Blood. 116: 3769-3769 |
| Pien GC, Basner-Tschakarjan E, Hui DJ, et al. (2009) Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors. The Journal of Clinical Investigation. 119: 1688-95 |
| Hui DJ, Pien GC, Basner-Tschakarjan E, et al. (2009) Suppression of CTL Responses against AAV-Capsid Epitopes by Peptide-Induced Regulatory T Cells. Blood. 114: 377-377 |
| Pien GC, Hasbrouck NC, Maus MV, et al. (2007) Quantifying Capsid Peptide:MHC I Complexes Following Adeno-Associated Virus (AAV) Transduction Blood. 110: 3737-3737 |
| Huang D, Shi FD, Jung S, et al. (2006) The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 896-905 |
| Pien GC, Nguyen KB, Malmgaard L, et al. (2002) A unique mechanism for innate cytokine promotion of T cell responses to viral infections. Journal of Immunology (Baltimore, Md. : 1950). 169: 5827-37 |
| Nguyen KB, Watford WT, Salomon R, et al. (2002) Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection. Science (New York, N.Y.). 297: 2063-6 |