Elizabeth A. Shakhnovich, Ph.D.

Affiliations: 
2007 Harvard University, Cambridge, MA, United States 
Area:
Microbiology Biology
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"Elizabeth Shakhnovich"

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John J. Mekalanos grad student 2007 Harvard
 (Small molecules as novel probes for understanding Vibrio cholerae virulence mechanisms and regulation in vitro and in vivo.)
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Publications

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Yamaichi Y, Duigou S, Shakhnovich EA, et al. (2009) Targeting the replication initiator of the second Vibrio chromosome: towards generation of vibrionaceae-specific antimicrobial agents. Plos Pathogens. 5: e1000663
Shakhnovich EA, Davis BM, Waldor MK. (2009) Hfq negatively regulates type III secretion in EHEC and several other pathogens. Molecular Microbiology. 74: 347-63
Shakhnovich EA, Sturtevant D, Mekalanos JJ. (2007) Molecular mechanisms of virstatin resistance by non-O1/non-O139 strains of Vibrio cholerae. Molecular Microbiology. 66: 1331-41
Shakhnovich EA, Hung DT, Pierson E, et al. (2007) Virstatin inhibits dimerization of the transcriptional activator ToxT Proceedings of the National Academy of Sciences of the United States of America. 104: 2372-2377
Hung DT, Shakhnovich EA, Pierson E, et al. (2005) Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization. Science (New York, N.Y.). 310: 670-4
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