Victoria B. Rodriguez, Ph.D.

Affiliations: 
2012 Bioengineering University of Washington, Seattle, Seattle, WA 
Area:
Biomedical Engineering, Microbiology Biology
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"Victoria Rodriguez"

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Wendy Thomas grad student 2012 University of Washington
 (Escherichia coli's literal link to infection: Exploring mutagenesis of the FimH adhesin to allosterically "lock" in low-affinity.)
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Publications

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Kisiela DI, Avagyan H, Friend D, et al. (2015) Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coli. Plos Pathogens. 11: e1004857
Kisiela DI, Avagyan H, Friend D, et al. (2015) The overlap between the FimH pocket residues and mAb926 and mAb475 epitopes. Plos Pathogens
Kisiela DI, Avagyan H, Friend D, et al. (2015) Effect of mannose on antibodies bound to FimH as determined by surface plasmon resonance. Plos Pathogens
Kisiela DI, Avagyan H, Friend D, et al. (2015) Effect of mannose on antibody binding. Plos Pathogens
Kisiela DI, Rodriguez VB, Tchesnokova V, et al. (2013) Conformational inactivation induces immunogenicity of the receptor-binding pocket of a bacterial adhesin. Proceedings of the National Academy of Sciences of the United States of America. 110: 19089-94
Rodriguez VB, Kidd BA, Interlandi G, et al. (2013) Allosteric coupling in the bacterial adhesive protein FimH. The Journal of Biological Chemistry. 288: 24128-39
Le Trong I, Aprikian P, Kidd BA, et al. (2010) Structural basis for mechanical force regulation of the adhesin FimH via finger trap-like beta sheet twisting. Cell. 141: 645-55
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