Michael L. Sinnott

Affiliations: 
1987 University of Bristol, Bristol, England, United Kingdom 
 1987-1996 University of Illinois at Chicago, Chicago, IL, United States 
 1996-2003 Institute of Science and Technology The University of Manchester, Manchester, England, United Kingdom 
 2003- University of Huddersfield 
Area:
Organic chemistry
Website:
https://www.hud.ac.uk/ourstaff/profile/index.php?staffuid=sappmls
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"Michael L. Sinnott"
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DOI: 10.1021/jo01263a095

Mean distance: 19.36
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Mark C. Whiting grad student 1968 University of Bristol (Chemistry Tree)

Children

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Andrew Bennet grad student University of Huddersfield (Chemistry Tree)
Stephen G. Withers grad student 1977 University of Bristol (Chemistry Tree)
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Publications

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Neustroev KN, Golubev AM, Sinnott ML, et al. (2006) Transferase and hydrolytic activities of the laminarinase from Rhodothermus marinus and its M133A, M133C, and M133W mutants. Glycoconjugate Journal. 23: 501-11
Baty JW, Sinnott ML. (2005) The kinetics of the spontaneous, proton- and AlIII-catalysed hydrolysis of 1,5-anhydrocellobiitol - Models for cellulose depolymerization in paper aging and alkaline pulping, and a benchmark for cellulase efficiency Canadian Journal of Chemistry. 83: 1516-1524
Baty J, Sinnott ML. (2004) Efficient electrophilic catalysis of 1,5-anhydrocellobiitol hydrolysis by AlIII; implications for the conservation of "rosin-alum" sized paper Chemical Communications. 10: 866-867
von Ossowski I, Ståhlberg J, Koivula A, et al. (2003) Engineering the exo-loop of Trichoderma reesei cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D. Journal of Molecular Biology. 333: 817-29
Koivula A, Ruohonen L, Wohlfahrt G, et al. (2002) The active site of cellobiohydrolase Cel6A from Trichoderma reesei: the roles of aspartic acids D221 and D175. Journal of the American Chemical Society. 124: 10015-24
Becker D, Braet C, Brumer H, et al. (2001) Engineering of a glycosidase Family 7 cellobiohydrolase to more alkaline pH optimum: the pH behaviour of Trichoderma reesei Cel7A and its E223S/ A224H/L225V/T226A/D262G mutant. The Biochemical Journal. 356: 19-30
Hart DO, He S, Chany CJ, et al. (2000) Identification of Asp-130 as the catalytic nucleophile in the main alpha-galactosidase from Phanerochaete chrysosporium, a family 27 glycosyl hydrolase. Biochemistry. 39: 9826-36
Zhao Y, Sinnott ML. (2000) A new affinity ligand for the isolation of a single 'feruloyl esterase' (FAE-III) from Aspergillus niger. Bioorganic & Medicinal Chemistry. 8: 917-24
Andrews SR, Charnock SJ, Lakey JH, et al. (2000) Substrate specificity in glycoside hydrolase family 10. Tyrosine 87 and leucine 314 play a pivotal role in discriminating between glucose and xylose binding in the proximal active site of Pseudomonas cellulosa xylanase 10A. The Journal of Biological Chemistry. 275: 23027-33
Becker D, Johnson KS, Koivula A, et al. (2000) Hydrolyses of alpha- and beta-cellobiosyl fluorides by Cel6A (cellobiohydrolase II) of Trichoderma reesei and Humicola insolens. The Biochemical Journal. 345: 315-9
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