Homme W. Hellinga
Affiliations: | Duke University, Durham, NC |
Area:
BiochemistryGoogle:
"Homme Hellinga"Mean distance: 4976.62
Children
Sign in to add traineeJonathan S. Marvin | grad student | 2001 | Duke |
Michael S. Wisz | grad student | 2002 | Duke |
Mary A. Dwyer | grad student | 2004 | Duke |
Shahir S. Rizk | grad student | 2006 | Duke |
Matthew J. Cuneo | grad student | 2007 | Duke |
Aleksandr E. Miklos | grad student | 2008 | Duke |
Curtis J. Layton | grad student | 2010 | Duke |
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Publications
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Allert MJ, Kumar S, Wang Y, et al. (2023) Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching. Communications Chemistry. 6: 168 |
Allert MJ, Hellinga HW. (2022) Discovery of Thermostable, Fluorescently Responsive Glucose Biosensors by Structure-Assisted Function Extrapolation. Biochemistry. 61: 276-293 |
Allert MJ, Hellinga HW. (2020) Harnessing environmental Ca for extracellular protein thermostabilization. Biochemistry |
Allert MJ, Hellinga HW. (2020) Describing complex structure-function relationships in biomolecules at equilibrium. Journal of Molecular Biology |
Shi Y, Hellinga HW, Beese LS. (2017) Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proceedings of the National Academy of Sciences of the United States of America |
Mabanglo MF, Hast MA, Lubock NB, et al. (2014) Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design. Protein Science : a Publication of the Protein Society. 23: 289-301 |
Grimley JS, Li L, Wang W, et al. (2013) Visualization of synaptic inhibition with an optogenetic sensor developed by cell-free protein engineering automation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16297-309 |
Wang W, Wu EY, Hellinga HW, et al. (2012) Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. The Journal of Biological Chemistry. 287: 28215-26 |
Hast MA, Nichols CB, Armstrong SM, et al. (2011) Structures of Cryptococcus neoformans protein farnesyltransferase reveal strategies for developing inhibitors that target fungal pathogens. The Journal of Biological Chemistry. 286: 35149-62 |
Layton CJ, Hellinga HW. (2011) Integration of cell-free protein coexpression with an enzyme-linked immunosorbent assay enables rapid analysis of protein-protein interactions directly from DNA. Protein Science : a Publication of the Protein Society. 20: 1432-8 |