Zachary T. Cusumano, Ph.D.
Affiliations: | 2012 | Biology & Biomedical Sciences (Biochemistry) | Washington University, Saint Louis, St. Louis, MO |
Area:
Microbiology Biology, Biochemistry, GeneticsGoogle:
"Zachary Cusumano"Parents
Sign in to add mentor| Michael G. Caparon | grad student | 2012 | Washington University | |
| (The Convergence of Metabolism and Virulence Factor Regulation on Streptococcus pyogenes Pathogenesis.) | ||||
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Publications
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| Klein RD, Shu Q, Cusumano ZT, et al. (2018) Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation. Mbio. 9 |
| Xu W, Flores-Mireles AL, Cusumano ZT, et al. (2017) Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection. Npj Biofilms and Microbiomes. 3: 28 |
| Spaulding CN, Klein RD, Ruer S, et al. (2017) Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist. Nature |
| Port GC, Cusumano ZT, Tumminello PR, et al. (2017) SpxA1 and SpxA2 Act Coordinately To Fine-Tune Stress Responses and Virulence in Streptococcus pyogenes. Mbio. 8 |
| Mydock-McGrane L, Cusumano Z, Han Z, et al. (2016) Anti-virulence C-mannoisdes as antibiotic-sparing, oral therapeutics for urinary tract infections. Journal of Medicinal Chemistry |
| Shu Q, Krezel AM, Cusumano ZT, et al. (2016) Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation. Proceedings of the National Academy of Sciences of the United States of America |
| Cusumano ZT, Klein RD, Hultgren SJ. (2016) Innovative Solutions to Sticky Situations: Antiadhesive Strategies for Treating Bacterial Infections. Microbiology Spectrum. 4 |
| Patel MB, Garrad EC, Stavri A, et al. (2016) Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. Bioorganic & Medicinal Chemistry |
| Jarvis C, Han Z, Kalas V, et al. (2016) Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI. Chemmedchem |
| Mydock-McGrane LK, Cusumano ZT, Janetka JW. (2015) Mannose-Derived FimH Antagonists: A promising anti-virulence therapeutic strategy for Urinary Tract Infections and Crohn's Disease. Expert Opinion On Therapeutic Patents |