Qing Lou, Ph.D.

Affiliations: 
2011 Biomedical Engineering Washington University, Saint Louis, St. Louis, MO 
Area:
Biomedical Engineering
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"Qing Lou"

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Igor R. Efimov grad student 2011 Washington University
 (Cardiac Remodeling Of Conduction, Repolarization and Excitation-Contraction Coupling: From Animal Model to Failing Human Heart.)
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Publications

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Munger MA, Olğar Y, Koleske ML, et al. (2020) Tetrodotoxin-Sensitive Neuronal-Type Na Channels: A Novel and Druggable Target for Prevention of Atrial Fibrillation. Journal of the American Heart Association. e015119
Liu B, Lou Q, Smith H, et al. (2020) Conditional Up-Regulation of SERCA2a Exacerbates RyR2-Dependent Ventricular and Atrial Arrhythmias. International Journal of Molecular Sciences. 21
Liu B, Ho HT, Brunello L, et al. (2015) Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT. Cardiovascular Research
Radwa?ski PB, Brunello L, Veeraraghavan R, et al. (2015) Neuronal Na+ channel blockade suppresses arrhythmogenic diastolic Ca2+ release. Cardiovascular Research. 106: 143-52
Lou Q, Belevych AE, Radwański PB, et al. (2015) Alternating membrane potential/calcium interplay underlies repetitive focal activity in a genetic model of calcium-dependent atrial arrhythmias. The Journal of Physiology. 593: 1443-58
Glukhov AV, Kalyanasundaram A, Lou Q, et al. (2015) Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1. European Heart Journal. 36: 686-97
Belevych A, Ho H, Lou Q, et al. (2015) Properties of Atrial Myocyte Calcium Handling in Canine Model of Chronic Heart Failure Biophysical Journal. 108: 419a
Bonilla IM, Long VP, Vargas-Pinto P, et al. (2014) Calcium-activated potassium current modulates ventricular repolarization in chronic heart failure. Plos One. 9: e108824
Lou Q, Hansen BJ, Fedorenko O, et al. (2014) Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping. Circulation. 130: 315-24
Liu B, Ho HT, Velez-Cortes F, et al. (2014) Genetic ablation of ryanodine receptor 2 phosphorylation at Ser-2808 aggravates Ca(2+)-dependent cardiomyopathy by exacerbating diastolic Ca2+ release. The Journal of Physiology. 592: 1957-73
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