Michael C. Chang, Ph.D.

Affiliations: 
Neuroscience Genentech, Inc., San Francisco, CA, United States 
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"Michael Chang"
Mean distance: 14.29 (cluster 11)
 
SNBCP

Parents

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Paul F. Worley grad student 2003-2011 Johns Hopkins
 (Narp regulates excitatory synaptic strength on parvalbumin-expressing interneurons.)
Morgan Sheng post-doc 2011-2016 Genentech, Inc.
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Publications

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Dejanovic B, Wu T, Tsai MC, et al. (2022) Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models. Nature Aging. 2: 837-850
Wu T, Dejanovic B, Gandham VD, et al. (2019) Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy. Cell Reports. 28: 2111-2123.e6
Chang MC, Srinivasan K, Friedman BA, et al. (2017) Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation. The Journal of Experimental Medicine
Gu Y, Huang S, Chang MC, et al. (2013) Obligatory role for the immediate early gene NARP in critical period plasticity. Neuron. 79: 335-46
Chang MC, Park JM, Pelkey KA, et al. (2010) Narp regulates homeostatic scaling of excitatory synapses on parvalbumin-expressing interneurons. Nature Neuroscience. 13: 1090-7
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