Ishraq Alim

Affiliations: 
Queen's University, Kingston, ON, Canada 
Area:
Electrophysiology
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"Ishraq Alim"
Mean distance: 17.15 (cluster 6)
 
SNBCP

Parents

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Martin R. Ralph research assistant 2004-2005 University of Toronto
Paul W. Frankland research assistant 2005-2006 University of Toronto
Alastair V. Ferguson grad student 2006- Queens University
Michael Tymianski grad student 2014 University of Toronto
 (Modulation of N-Methyl-D-Asparate Receptor by Transient Receptor Potential Melastatin Type-2 Regulates Neuronal Vulnerability to Ischemic Cell Death.)
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Publications

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Alim I, Caulfield JT, Chen Y, et al. (2019) Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke. Cell
Alim I, Karuppagounder SS, Ratan RR. (2017) Ischemia Regulated Transcription Factors: Hypoxia Inducible Factor 1 and Activating Transcription Factor 4 Primer On Cerebrovascular Diseases. 250-255
Neitemeier S, Dolga AM, Honrath B, et al. (2016) Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis. Cell Death & Disease. 7: e2214
Karuppagounder SS, Alim I, Khim SJ, et al. (2016) Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Science Translational Medicine. 8: 328ra29
Neitemeier S, Dolga AM, Honrath B, et al. (2016) Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis Cell Death and Disease. 7
Karuppagounder SS, Kumar A, Shao DS, et al. (2015) Metabolism and epigenetics in the nervous system: Creating cellular fitness and resistance to neuronal death in neurological conditions via modulation of oxygen-, iron-, and 2-oxoglutarate-dependent dioxygenases. Brain Research
Karuppagounder SS, Kumar A, Shao DS, et al. (2015) Metabolism and epigenetics in the nervous system: Creating cellular fitness and resistance to neuronal death in neurological conditions via modulation of oxygen-, iron-, and 2-oxoglutarate-dependent dioxygenases Brain Research
Alim I, Haskew-Layton RE, Aleyasin H, et al. (2014) Spatial, temporal, and quantitative manipulation of intracellular hydrogen peroxide in cultured cells. Methods in Enzymology. 547: 251-73
Alim I, Teves L, Li R, et al. (2013) Modulation of NMDAR subunit expression by TRPM2 channels regulates neuronal vulnerability to ischemic cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17264-77
Alim I, Fry WM, Walsh MH, et al. (2010) Actions of adiponectin on the excitability of subfornical organ neurons are altered by food deprivation. Brain Research. 1330: 72-82
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