Patricia Brown

Neuroscience McGill University, Montreal, QC, Canada 
Excitatory and Inhibitory Ligand-Gated Ion Channels
"Patricia Brown"
Mean distance: 16.65 (cluster 11)
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Brown PMGE, McGuire H, Bowie D. (2017) Stargazin and cornichon-3 relieve polyamine block of AMPA receptors by enhancing blocker permeation. The Journal of General Physiology
Paramo T, Brown PMGE, Musgaard M, et al. (2017) Functional Validation of Heteromeric Kainate Receptor Models. Biophysical Journal
Krogsgaard-Larsen N, Delgar CG, Koch K, et al. (2016) Design and Synthesis of a Series of l-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid. Journal of Medicinal Chemistry
Brown PM, Aurousseau MR, Musgaard M, et al. (2015) Kainate receptor pore-forming and auxiliary subunits regulate channel block by a novel mechanism. The Journal of Physiology
Accardi MV, Brown PM, Miraucourt LS, et al. (2015) α6-Containing GABAA Receptors Are the Principal Mediators of Inhibitory Synapse Strengthening by Insulin in Cerebellar Granule Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9676-88
Demmer CS, Møller C, Brown PM, et al. (2015) Binding Mode of an α-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1. Acs Chemical Neuroscience. 6: 845-54
Penna A, Wang DS, Yu J, et al. (2014) Hydrogen peroxide increases GABAA receptor-mediated tonic current in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10624-34
Accardi MV, Daniels BA, Brown PM, et al. (2014) Mitochondrial reactive oxygen species regulate the strength of inhibitory GABA-mediated synaptic transmission. Nature Communications. 5: 3168
Lachance-Touchette P, Brown P, Meloche C, et al. (2011) Novel α1 and γ2 GABAA receptor subunit mutations in families with idiopathic generalized epilepsy. The European Journal of Neuroscience. 34: 237-49
Fay AM, Corbeil CR, Brown P, et al. (2009) Functional characterization and in silico docking of full and partial GluK2 kainate receptor agonists. Molecular Pharmacology. 75: 1096-107
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