Brigit E. Riley, Ph.D.

Affiliations: 
2004 University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biochemistry
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"Brigit Riley"
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Harry T. Orr grad student 2004 UMN
 (The coupling of ubiquitin -like proteins and the neurodegenerative disease protein, ataxin -1.)
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Publications

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Klionsky DJ, Abdelmohsen K, Abe A, et al. (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222
Riley BE, Gardai SJ, Emig-Agius D, et al. (2014) Systems-based analyses of brain regions functionally impacted in Parkinson's disease reveals underlying causal mechanisms. Plos One. 9: e102909
Hipp MS, Patel CN, Bersuker K, et al. (2012) Indirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease. The Journal of Cell Biology. 196: 573-87
Kaiser SE, Riley BE, Shaler TA, et al. (2011) Protein standard absolute quantification (PSAQ) method for the measurement of cellular ubiquitin pools. Nature Methods. 8: 691-6
Riley BE, Kaiser SE, Kopito RR. (2011) Autophagy inhibition engages Nrf2-p62 Ub-associated signaling. Autophagy. 7: 338-40
Riley BE, Kaiser SE, Shaler TA, et al. (2010) Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. The Journal of Cell Biology. 191: 537-52
Riley BE, Orr HT. (2006) Polyglutamine neurodegenerative diseases and regulation of transcription: assembling the puzzle. Genes & Development. 20: 2183-92
Iwata A, Riley BE, Johnston JA, et al. (2005) HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. The Journal of Biological Chemistry. 280: 40282-92
Riley BE, Zoghbi HY, Orr HT. (2005) SUMOylation of the polyglutamine repeat protein, ataxin-1, is dependent on a functional nuclear localization signal. The Journal of Biological Chemistry. 280: 21942-8
Riley BE, Xu Y, Zoghbi HY, et al. (2004) The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up. The Journal of Biological Chemistry. 279: 42290-301
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