Deborah H. Spector

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Microbiology Biology
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"Deborah Spector"

Children

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Anita K. McElroy grad student 2000 UCSD
Kristine E. Yoder grad student 2000 UCSD
Elizabeth A. White grad student 2007 UCSD
Anokhi J. Kapasi grad student 2008 UCSD
Karen Tran grad student 2009 UCSD
Sarah W. Burgdorf grad student 2012 UCSD
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Publications

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Branche E, Wang YT, Viramontes KM, et al. (2022) SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus. Nature Communications. 13: 5341
Clark AE, Zhu Z, Krach F, et al. (2020) Zika virus is transmitted in neural progenitor cells via cell-to-cell spread and infection is inhibited by the autophagy inducer trehalose. Journal of Virology
Bernstein DI, Morello CS, Cardin RD, et al. (2019) A vaccine containing highly purified virus particles in adjuvant provides high level protection against genital infection and disease in guinea pigs challenged intravaginally with homologous and heterologous strains of herpes simplex virus type 2. Vaccine
Clark AE, Sabalza M, Gordts PLSM, et al. (2017) Human Cytomegalovirus Replication is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 Through Distinctively Different Mechanisms. Journal of Virology
Batra R, Stark TJ, Clark E, et al. (2016) RNA-binding protein CPEB1 remodels host and viral RNA landscapes. Nature Structural & Molecular Biology
Belzile JP, Sabalza M, Craig M, et al. (2015) Trehalose, an mTOR-Independent Inducer of Autophagy, Inhibits Human Cytomegalovirus Infection in Multiple Cell Types. Journal of Virology
Clark E, Spector DH. (2015) Studies on the Contribution of Human Cytomegalovirus UL21a and UL97 to Viral Growth and Inactivation of the Anaphase-Promoting Complex/Cyclosome (APC/C) E3 Ubiquitin Ligase Reveal a Unique Cellular Mechanism for Downmodulation of the APC/C Subunits APC1, APC4, and APC5. Journal of Virology. 89: 6928-39
Spector DH. (2015) Human cytomegalovirus riding the cell cycle. Medical Microbiology and Immunology. 204: 409-19
Spector DH. (2014) IUGR and congenital cytomegalovirus infection. The Journal of Infectious Diseases. 209: 1497-9
Belzile JP, Stark TJ, Yeo GW, et al. (2014) Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA. Journal of Virology. 88: 4021-39
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