Yasuhiro Tsume, Ph.D.

Affiliations: 
2006 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Pharmacology
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"Yasuhiro Tsume"
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Parents

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Gordon L. Amidon grad student 2006 University of Michigan
 (Floxuridine prodrug development: Transporter affinity and enzymatic activation.)
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Publications

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Tsume Y. (2023) Evaluation and prediction of oral drug absorption and bioequivalence with food-druginteraction. Drug Metabolism and Pharmacokinetics. 50: 100502
Hens B, Seegobin N, Bermejo M, et al. (2022) Dissolution Challenges Associated with the Surface pH of Drug Particles: Integration into Mechanistic Oral Absorption Modeling. The Aaps Journal. 24: 17
Gonzalez-Alvarez I, Bermejo M, Tsume Y, et al. (2021) An In Vivo Predictive Dissolution Methodology (iPD Methodology) with a BCS Class IIb Drug Can Predict the In Vivo Bioequivalence Results: Etoricoxib Products. Pharmaceutics. 13
Tsume Y, Patel S, Wang M, et al. (2020) The introduction of a new flexible in vivo predictive dissolution apparatus, GIS-alpha (GIS-α), to study dissolution profiles of BCS class IIb drugs, dipyridamole and ketoconazole. Journal of Pharmaceutical Sciences
Bermejo M, Hens B, Dickens J, et al. (2020) A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP. Pharmaceutics. 12
Hens B, Kataoka M, Ueda K, et al. (2020) Biopredictive in vitro testing methods to assess intestinal drug absorption from supersaturating dosage forms Journal of Drug Delivery Science and Technology. 56: 101275
Paixão P, Kawakami K, Bermejo M, et al. (2020) Report from the “3rd International Symposium on BA/BE of Oral Drug Products: Biopharmaceutics meets Galenics” Journal of Drug Delivery Science and Technology. 56: 101274
Tsume Y, Igawa N, Drelich AJ, et al. (2020) The in vivo predictive dissolution for immediate release dosage of donepezil and danazol, BCS class IIc drugs, with the GIS and the USP II with biphasic dissolution apparatus Journal of Drug Delivery Science and Technology. 56: 100920
Bermejo M, Kuminek G, Al-Gousous J, et al. (2019) Exploring Bioequivalence of Dexketoprofen Trometamol Drug Products with the Gastrointestinal Simulator (GIS) and Precipitation Pathways Analyses. Pharmaceutics. 11
Paixão P, Bermejo M, Hens B, et al. (2018) Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State. Molecular Pharmaceutics
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