Michael J. Detke

MedAvante, Hamilton Township, NJ, United States 
Drug development
"Michael Detke"
Mean distance: 16.35 (cluster 19)


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Irwin Lucki grad student 1992-1996 Penn
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Chappell JC, Eisenhofer G, Owens MJ, et al. (2014) Effects of duloxetine on norepinephrine and serotonin transporter activity in healthy subjects. Journal of Clinical Psychopharmacology. 34: 9-16
Trivedi MH, Desaiah D, Ossanna MJ, et al. (2008) Clinical evidence for serotonin and norepinephrine reuptake inhibition of duloxetine. International Clinical Psychopharmacology. 23: 161-9
Bymaster FP, Lee TC, Knadler MP, et al. (2005) The dual transporter inhibitor duloxetine: a review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression. Current Pharmaceutical Design. 11: 1475-93
Carlezon WA, Pliakas AM, Parow AM, et al. (2002) Antidepressant-like effects of cytidine in the forced swim test in rats. Biological Psychiatry. 51: 882-9
Chalon S, Bieck PR, Goldstein DJ, et al. (2002) The tyramine pressor test may have limited sensitivity, especially in the presence of dual serotonin/norepinephrine uptake inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 698-9; author reply
Page ME, Detke MJ, Dalvi A, et al. (1999) Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test. Psychopharmacology. 147: 162-7
Detke MJ, Johnson J, Lucki I. (1997) Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression. Experimental and Clinical Psychopharmacology. 5: 107-12
Detke MJ, Lucki I. (1996) Detection of serotonergic and noradrenergic antidepressants in the rat forced swimming test: the effects of water depth. Behavioural Brain Research. 73: 43-6
Detke MJ, Rickels M, Lucki I. (1995) Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology. 121: 66-72
Detke MJ, Wieland S, Lucki I. (1995) Blockade of the antidepressant-like effects of 8-OH-DPAT, buspirone and desipramine in the rat forced swim test by 5HT1A receptor antagonists. Psychopharmacology. 119: 47-54
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