Juan Carlos Saez
Affiliations: | Physiology | P. Universidad Catolica de Chile, Santiago, Región Metropolitana, Chile |
Area:
connexin, pannexinGoogle:
"Juan Saez"Bio:
RESEARCH
Regulation and function of connexin and pannexin based membrane channels in cells of the nervous and immune and systems and their involvement in pathological conditions.
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Mean distance: 15.68 (cluster 16) | S | N | B | C | P |
Children
Sign in to add trainee| Fernando B. Avila-Rencoret | research assistant | 2001-2006 | P. Universidad Catolica de Chile |
| Nicolas Palacios-Prado | research assistant | 2003-2007 | P. Universidad Catolica de Chile |
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Publications
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| García-Rodríguez C, Duarte Y, Ardiles ÁO, et al. (2024) The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes. Journal of Neurochemistry |
| Abudara V, Araneda RC, Barrio L, et al. (2024) Remembrances of Dr. Michael V.L. Bennett by Iberoamerican Colleagues and Friends. Neuroscience |
| Li H, Guo A, Salgado M, et al. (2023) The connexin hemichannel inhibitor D4 produces rapid antidepressant-like effects in mice. Journal of Neuroinflammation. 20: 191 |
| Güiza J, Solís F, Valenzuela B, et al. (2023) Unnexin is a protein subunit of a large-pore channel expressed by unicellular organisms. Proceedings of the National Academy of Sciences of the United States of America. 120: e2307898120 |
| Vega JL, Gutiérrez C, Rojas M, et al. (2023) Contribution of large-pore channels to inflammation induced by microorganisms. Frontiers in Cell and Developmental Biology. 10: 1094362 |
| Abbott AC, García IE, Villanelo F, et al. (2023) Expression of KID syndromic mutation Cx26S17F produces hyperactive hemichannels in supporting cells of the organ of Corti. Frontiers in Cell and Developmental Biology. 10: 1071202 |
| Guo A, Zhang H, Li H, et al. (2022) Inhibition of connexin hemichannels alleviates neuroinflammation and hyperexcitability in temporal lobe epilepsy. Proceedings of the National Academy of Sciences of the United States of America. 119: e2213162119 |
| Lucero CM, Marambio-Ruiz L, Balmazabal J, et al. (2022) TNF-α Plus IL-1β Induces Opposite Regulation of Cx43 Hemichannels and Gap Junctions in Mesangial Cells through a RhoA/ROCK-Dependent Pathway. International Journal of Molecular Sciences. 23 |
| Palacios-Prado N, Soto PA, López X, et al. (2022) Endogenous pannexin1 channels form functional intercellular cell-cell channels with characteristic voltage-dependent properties. Proceedings of the National Academy of Sciences of the United States of America. 119: e2202104119 |
| López X, Palacios-Prado N, Güiza J, et al. (2021) A physiologic rise in cytoplasmic calcium ion signal increases pannexin1 channel activity via a C-terminus phosphorylation by CaMKII. Proceedings of the National Academy of Sciences of the United States of America. 118 |