Peter Århem
Affiliations: | Karolinska Institute, Stockholm, Sweden |
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"Peter Århem"Mean distance: 15.11 (cluster 40) | S | N | B | C | P |
Parents
Sign in to add mentor| Clay M. Armstrong | grad student | Karolinska | |
| Bernhard Frankenhaeuser | grad student | Karolinska |
Children
Sign in to add trainee| Fredrik Elinder | grad student | Linköping University | |
| Staffan Johansson | grad student | Umeå University | |
| Göran Klement | grad student | AstraZeneca | |
| Johanna Nilsson | grad student | Karolinska | |
| Kristoffer Sahlholm | grad student | Karolinska | |
| Hugo Zeberg | grad student | Karolinska |
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Publications
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| Ågren R, Zeberg H, Maciej Stępniewski T, et al. (2020) A ligand with two modes of interaction with the dopamine D2 receptor - An induced-fit mechanism of insurmountable antagonism. Acs Chemical Neuroscience |
| Ågren R, Nilsson J, Århem P. (2019) Closed and open state dependent block of potassium channels cause opposing effects on excitability - a computational approach. Scientific Reports. 9: 8175 |
| Ågren R, Århem P, Nilsson J, et al. (2018) The beta-arrestin-biased dopamine D2 receptor ligand, UNC9994, is a partial agonist at G-protein-mediated potassium channel activation. The International Journal of Neuropsychopharmacology |
| Zeberg H, Nilsson J, Århem P. (2018) The Importance of the Dissociation Rate in Ion Channel Blocking. Frontiers in Cellular Neuroscience. 12: 33 |
| Ågren R, Sahlholm K, Nilsson J, et al. (2018) Point mutation of a conserved aspartate, D69, in the muscarinic M2 receptor does not modify voltage-sensitive agonist potency. Biochemical and Biophysical Research Communications |
| Elinder F, Madeja M, Zeberg H, et al. (2016) Extracellular Linkers Completely Transplant the Voltage Dependence from Kv1.2 Ion Channels to Kv2.1. Biophysical Journal. 111: 1679-1691 |
| Sahlholm K, Zeberg H, Nilsson J, et al. (2016) The fast-off hypothesis revisited: A functional kinetic study of antipsychotic antagonism of the dopamine D2 receptor. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology |
| Lyu C, Mulder J, Barde S, et al. (2015) G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy. Molecular Pain. 11: 44 |
| Zeberg H, Robinson HP, Århem P. (2015) Density of voltage-gated potassium channels is a bifurcation parameter in pyramidal neurons. Journal of Neurophysiology. 113: 537-49 |
| Sahlholm K, Marcellino D, Nilsson J, et al. (2014) Typical and atypical antipsychotics do not differ markedly in their reversibility of antagonism of the dopamine D2 receptor. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 149-55 |