Göran Klement

Affiliations: 
AstraZeneca LP, Canóvanas, Canóvanas, Puerto Rico 
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"Göran Klement"
Mean distance: 17.13 (cluster 40)
 
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Publications

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Heusser SA, Yoluk Ö, Klement G, et al. (2016) Functional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel. Journal of Neurochemistry
Yoluk Ö, Heusser S, Pouya I, et al. (2015) Opening and Selectivity of the Glic Ligand-Gated Ion Channel can be Tuned by Mutation of Hydrophobic Residues in the Pore Biophysical Journal. 108: 431a
Yoluk O, Riederer EA, Andersson M, et al. (2014) Contribution of Structural Elements to Activation and Allosteric Modulation in an Anionic Ligand-Gated Ion Channel Biophysical Journal. 106: 547a
Klement G, Pouya I, Yoluk Ö, et al. (2014) Ligand-Gated Ion Channel Gating Kinetics and the Opening/Closing Mechanism are Sensitive to Mutations Altering the Hydrophobicity of the Ion Conduction Pore Biophysical Journal. 106: 343a
Nyman E, Franzén B, Nolting A, et al. (2013) In vitro pharmacological characterization of a novel TRPA1 antagonist and proof of mechanism in a human dental pulp model. Journal of Pain Research. 6: 59-70
Klement G, Druzin M, Haage D, et al. (2010) Spontaneous ryanodine-receptor-dependent Ca2+-activated K+ currents and hyperpolarizations in rat medial preoptic neurons. Journal of Neurophysiology. 103: 2900-11
Klement G, Nilsson J, Arhem P, et al. (2008) A tyrosine substitution in the cavity wall of a k channel induces an inverted inactivation. Biophysical Journal. 94: 3014-22
Bränström R, Leibiger IB, Leibiger B, et al. (2007) Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif. Diabetologia. 50: 1670-7
Arhem P, Klement G, Blomberg C. (2006) Channel density regulation of firing patterns in a cortical neuron model. Biophysical Journal. 90: 4392-404
Persson AS, Klement G, Almgren M, et al. (2005) A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction. Bmc Neuroscience. 6: 65
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