Göran Klement

Affiliations: 
AstraZeneca LP, Canóvanas, Canóvanas, Puerto Rico 
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"Göran Klement"
Mean distance: 17.13 (cluster 40)
 
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Publications

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Klement G, Eisele L, Malinowsky D, et al. (2013) Characterization of a ligand binding site in the human transient receptor potential ankyrin 1 pore. Biophysical Journal. 104: 798-806
Nyman E, Franzén B, Nolting A, et al. (2013) In vitro pharmacological characterization of a novel TRPA1 antagonist and proof of mechanism in a human dental pulp model. Journal of Pain Research. 6: 59-70
Klement G, Babich O, Larsson O, et al. (2012) Identification of novel NaV1.7 antagonists using high throughput screening platforms. Combinatorial Chemistry & High Throughput Screening. 15: 713-20
Klement G, Druzin M, Haage D, et al. (2010) Spontaneous ryanodine-receptor-dependent Ca2+-activated K+ currents and hyperpolarizations in rat medial preoptic neurons. Journal of Neurophysiology. 103: 2900-11
Klement G, Nilsson J, Arhem P, et al. (2008) A tyrosine substitution in the cavity wall of a k channel induces an inverted inactivation. Biophysical Journal. 94: 3014-22
Bränström R, Leibiger IB, Leibiger B, et al. (2007) Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif. Diabetologia. 50: 1670-7
Arhem P, Klement G, Blomberg C. (2006) Channel density regulation of firing patterns in a cortical neuron model. Biophysical Journal. 90: 4392-404
Persson AS, Klement G, Almgren M, et al. (2005) A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction. Bmc Neuroscience. 6: 65
Petersson S, Persson AS, Johansen JE, et al. (2003) Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly. The European Journal of Neuroscience. 18: 3231-40
Arhem P, Klement G, Nilsson J. (2003) Mechanisms of anesthesia: towards integrating network, cellular, and molecular level modeling. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: S40-7
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