Michael Brandt

Affiliations: 
Janssen Research & Development 
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"Michael Brandt"
Mean distance: 17.13 (cluster 19)
 
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Publications

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Parsons WH, Calvo RR, Cheung W, et al. (2015) Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]-1H-benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep). Journal of Medicinal Chemistry. 58: 3859-74
Winters MP, Subasinghe N, Wall M, et al. (2014) Discovery and SAR of a novel series of 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles as N-type calcium channel inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 2057-61
Winters MP, Subasinghe N, Wall M, et al. (2014) Discovery and SAR of novel tetrahydropyrrolo[3,4-c]pyrazoles as inhibitors of the N-type calcium channel. Bioorganic & Medicinal Chemistry Letters. 24: 2053-6
Zhu B, Xia M, Xu X, et al. (2013) Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists. Bioorganic & Medicinal Chemistry Letters. 23: 2234-7
Brandt MR, Beyer CE, Stahl SM. (2012) TRPV1 Antagonists and Chronic Pain: Beyond Thermal Perception. Pharmaceuticals (Basel, Switzerland). 5: 114-32
Subasinghe NL, Wall MJ, Winters MP, et al. (2012) A novel series of pyrazolylpiperidine N-type calcium channel blockers. Bioorganic & Medicinal Chemistry Letters. 22: 4080-3
Matthews JM, Qin N, Colburn RW, et al. (2012) The design and synthesis of novel, phosphonate-containing transient receptor potential melastatin 8 (TRPM8) antagonists. Bioorganic & Medicinal Chemistry Letters. 22: 2922-6
Codd EE, Baker J, Brandt MR, et al. (2010) Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 493-504
Codd EE, Ma J, Zhang SP, et al. (2010) Ex vivo delta opioid receptor autoradiography: CNS receptor occupancy of two novel compounds over their antihyperalgesic dose range. Pharmacology, Biochemistry, and Behavior. 96: 130-5
Baudy RB, Butera JA, Abou-Gharbia MA, et al. (2009) Prodrugs of perzinfotel with improved oral bioavailability. Journal of Medicinal Chemistry. 52: 771-8
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