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Jeremy R. Knowles

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
enzyme catalysis
Website:
http://www.thecrimson.com/article/2008/4/4/jeremy-r-knowles-jeremy-r-knowles/
Google:
"Jeremy Knowles"
Bio:

(1935 - 2008)
http://www.nasonline.org/member-directory/deceased-members/8887.html

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Parents

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Richard O. C. Norman grad student 1959-1961 Oxford
George S. Hammond post-doc 1961-1962 Caltech

Children

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James T. Kadonaga grad student Harvard (FlyTree)
Athel Cornish-Bowden grad student 1965-1967 Oxford
Peter F. Leadlay grad student 1974 Oxford
John A. Gatehouse grad student 1976 Oxford
Joshua Boger grad student 1973-1979 Harvard
Hagan P. Bayley grad student 1974-1979 Harvard
Stephen L. Buchwald grad student 1982 Harvard
Ronald T. Raines grad student 1986 Harvard
Jonathan J. Burbaum grad student 1982-1988 Harvard
Theodore S. Widlanski grad student 1989 Harvard
Stephen C. Blacklow grad student 1991 Harvard
Eugene G. Mueller grad student 1992 Harvard
George Orr post-doc Albert Einstein
Martin E. Tanner post-doc Harvard
George W. J. Fleet post-doc 1968-1969 Oxford
James V. Staros post-doc 1974-1977 Harvard
Christopher J. Easton post-doc 1980-1981 Harvard
John Wesley Frost post-doc 1981-1983 Harvard
Andreas Plückthun post-doc 1982-1985 Harvard
Timor Baasov post-doc 1986-1988 Harvard
Gary D. Glick post-doc 1990 Harvard
Elizabeth A. Komives post-doc 1987-1990 Harvard
David L. Pompliano post-doc 1988-1990 Harvard
Nicole S. Sampson post-doc 1991-1993 Harvard

Collaborators

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Publications

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Knowles J. (2003) Chemistry. Seeing is believing. Science (New York, N.Y.). 299: 2002-3
KNOWLES JR. (1996) THE ROLE OF METHIONINE IN ALPHA-CHYMOTRYPSIN-CATALYSED REACTIONS. The Biochemical Journal. 95: 180-90
Seidel HM, Knowles JR. (1994) Interaction of inhibitors with phosphoenolpyruvate mutase: implications for the reaction mechanism and the nature of the active site. Biochemistry. 33: 5641-6
Zhang Z, Sugio S, Komives EA, et al. (1994) Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution. Biochemistry. 33: 2830-7
Lodi PJ, Chang LC, Knowles JR, et al. (1994) Triosephosphate isomerase requires a positively charged active site: the role of lysine-12. Biochemistry. 33: 2809-14
Fanuel L, Granier B, Wilkin JM, et al. (1994) The precursor of the Streptomyces R61 DD-peptidase containing a C-terminal extension is inactive. Febs Letters. 351: 49-52
Anderson SR, Anderson VE, Knowles JR. (1994) Primary and secondary kinetic isotope effects as probes of the mechanism of yeast enolase. Biochemistry. 33: 10545-55
Gray JV, Knowles JR. (1994) Monofunctional chorismate mutase from Bacillus subtilis: FTIR studies and the mechanism of action of the enzyme. Biochemistry. 33: 9953-9
Lodi PJ, Knowles JR. (1993) Direct evidence for the exploitation of an alpha-helix in the catalytic mechanism of triosephosphate isomerase. Biochemistry. 32: 4338-43
Gallo KA, Knowles JR. (1993) Purification, cloning, and cofactor independence of glutamate racemase from Lactobacillus. Biochemistry. 32: 3981-90
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