Darell D. Bigner, M.D., Ph.D.
Affiliations: | Pathology and Surgery | Duke University, Durham, NC |
Area:
Neuro-OncologyWebsite:
http://pathology.mc.duke.edu/neuropath/np_faculty_dbigner.htmGoogle:
"Darell Bigner"Bio:
1989 AANP President
MD, Duke University, PhD, Duke University
http://www.cancer.duke.edu/btc/docs/general/1.Wpreuss.pdf
Mean distance: 20.63 (cluster 32)
Cross-listing: Neuropathology Tree
BETA: Related publications
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Publications
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Sun MA, Yang R, Liu H, et al. (2023) Repurposing Clemastine to Target Glioblastoma Cell Stemness. Cancers. 15 |
Thompson EM, Landi D, Brown MC, et al. (2023) Recombinant polio-rhinovirus immunotherapy for recurrent paediatric high-grade glioma: a phase 1b trial. The Lancet. Child & Adolescent Health |
Parker S, McDowall C, Sanchez-Perez L, et al. (2023) Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models. Science Translational Medicine. 15: eabn5649 |
Gromeier M, Brown MC, Zhang G, et al. (2021) Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy. Nature Communications. 12: 352 |
Mosaheb MM, Dobrikova EY, Brown MC, et al. (2020) Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity. Nature Communications. 11: 524 |
Desjardins A, Randazzo D, Chandramohan V, et al. (2020) Phase I trial of D2C7 immunotoxin (D2C7-IT) administered intratumorally via convection-enhanced delivery (CED) for recurrent malignant glioma (MG). Journal of Clinical Oncology. 38: 2566-2566 |
Chandramohan V, Bao X, Yu X, et al. (2019) Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations. Journal For Immunotherapy of Cancer. 7: 142 |
Hansen LJ, Sun R, Yang R, et al. (2019) MTAP loss promotes stemness in glioblastoma and confers unique susceptibility to purine starvation. Cancer Research |
Yu X, Dobrikov M, Keir ST, et al. (2019) Synergistic antitumor effects of 9.2.27-PE38KDEL and ABT-737 in primary and metastatic brain tumors. Plos One. 14: e0210608 |
Lipp ES, Healy P, Austin A, et al. (2019) MGMT: Immunohistochemical Detection in High-Grade Astrocytomas. Journal of Neuropathology and Experimental Neurology. 78: 57-64 |