Paul J. Muchowski

Affiliations: 
Neuroscience University of California, San Francisco, San Francisco, CA 
Area:
Neuroscience Biology, Immunology
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"Paul Muchowski"
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Children

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Wanda Kwan grad student 2011 UCSF
Angela M. Sia grad student 2013 UCSF
Justin Legleiter post-doc 2005-2008 UCSF (Chemistry Tree)
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Publications

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Aron R, Pellegrini P, Green EW, et al. (2020) Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease. Nature Communications. 11: 1065
Chen MZ, Mok SA, Ormsby AR, et al. (2017) N-Terminal Fragments of Huntingtin Longer than Residue 170 form Visible Aggregates Independently to Polyglutamine Expansion. Journal of Huntington's Disease
Larkin PB, Sathyasaikumar KV, Notarangelo FM, et al. (2016) Tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase 1 make separate, tissue-specific contributions to basal and inflammation-induced kynurenine pathway metabolism in mice. Biochimica Et Biophysica Acta
Oliveira AO, Osmand A, Outeiro TF, et al. (2016) αB-Crystallin over-expression in astrocytes modulates the phenotype of the BACHD mouse model of Huntington's disease. Human Molecular Genetics
Giorgini F, Huang SY, Sathyasaikumar KV, et al. (2013) Targeted deletion of kynurenine 3-monooxygenase in mice: a new tool for studying kynurenine pathway metabolism in periphery and brain. The Journal of Biological Chemistry. 288: 36554-66
Horne EA, Coy J, Swinney K, et al. (2013) Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models. The European Journal of Neuroscience. 37: 429-40
Sontag EM, Lotz GP, Yang G, et al. (2012) Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules. Journal of Huntington's Disease. 1: 127-40
Bouchard J, Truong J, Bouchard K, et al. (2012) Cannabinoid receptor 2 signaling in peripheral immune cells modulates disease onset and severity in mouse models of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 18259-68
Kwan W, Träger U, Davalos D, et al. (2012) Mutant huntingtin impairs immune cell migration in Huntington disease. The Journal of Clinical Investigation. 122: 4737-47
Larkin PB, Muchowski PJ. (2012) Genetic Deficiency of Complement Component 3 Does Not Alter Disease Progression in a Mouse Model of Huntington's Disease. Journal of Huntington's Disease. 1: 107-18
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