Davide Trotti

Neuroscience Thomas Jefferson University 
Neuroscience Biology
"Davide Trotti"
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Westergard T, McAvoy K, Russell K, et al. (2019) Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress. Embo Molecular Medicine
Kia A, McAvoy K, Krishnamurthy K, et al. (2018) Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha. Glia
Rosenblum LT, Trotti D. (2017) EAAT2 and the Molecular Signature of Amyotrophic Lateral Sclerosis. Advances in Neurobiology. 16: 117-136
Mohamed LA, Markandaiah S, Bonanno S, et al. (2017) Blood-Brain Barrier Driven Pharmacoresistance in Amyotrophic Lateral Sclerosis and Challenges for Effective Drug Therapies. The Aaps Journal
Rosenblum LT, Shamamandri-Markandaiah S, Ghosh B, et al. (2017) Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS. Experimental Neurology
Westergard T, Jensen BK, Wen X, et al. (2016) Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72-ALS/FTD. Cell Reports. 17: 645-652
Wen X, Westergard T, Pasinelli P, et al. (2016) Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene. Neuroscience Letters
Qosa H, Lichter J, Sarlo M, et al. (2016) Astrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P-Glycoprotein) in endothelial cells of the blood-brain barrier in mutant superoxide dismutase 1-linked amyotrophic lateral sclerosis. Glia
Qosa H, Miller DS, Pasinelli P, et al. (2015) Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders. Brain Research
Jablonski M, Miller DS, Pasinelli P, et al. (2015) ABC transporter-driven pharmacoresistance in Amyotrophic Lateral Sclerosis. Brain Research. 1607: 1-14
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