Robert Luedtke

Affiliations: 
Pharmacology and Neuroscience University of North Texas Health Science Center at Fort Worth 
Area:
Neuroscience Biology
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"Robert Luedtke"
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Publications

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Tian GL, Hsieh CJ, Taylor M, et al. (2023) Synthesis of bitopic ligands based on fallypride and evaluation of their affinity and selectivity towards dopamine D and D receptors. European Journal of Medicinal Chemistry. 261: 115751
Estrada-Sánchez AM, Rangel-Barajas C, Howe AG, et al. (2023) Selective Activation of D3 Dopamine Receptors Ameliorates DOI-Induced Head Twitching Accompanied by Changes in Corticostriatal Processing. International Journal of Molecular Sciences. 24
Gao RD, Taylor M, McInnis T, et al. (2023) Synthesis and Pharmacological Characterization of a Difluorinated Analogue of Reduced Haloperidol as a Sigma-1 Receptor Ligand. Acs Chemical Neuroscience
Kim HY, Lee JY, Hsieh CJ, et al. (2022) Design and Synthesis of Conformationally Flexible Scaffold as Bitopic Ligands for Potent D-Selective Antagonists. International Journal of Molecular Sciences. 24
Lee B, Taylor M, Griffin SA, et al. (2021) Evaluation of Substituted -Phenylpiperazine Analogs as D3 vs. D2 Dopamine Receptor Subtype Selective Ligands. Molecules (Basel, Switzerland). 26
Hayatshahi HS, Luedtke RR, Taylor M, et al. (2021) Factors Governing Selectivity of Dopamine Receptor Binding Compounds for D2R and D3R Subtypes. Journal of Chemical Information and Modeling
Hsieh CJ, Riad A, Lee JY, et al. (2021) Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods. Biomolecules. 11
Ågren R, Zeberg H, Maciej Stępniewski T, et al. (2020) A ligand with two modes of interaction with the dopamine D2 receptor - An induced-fit mechanism of insurmountable antagonism. Acs Chemical Neuroscience
Chen PJ, Taylor M, Griffin SA, et al. (2019) Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D receptor ligands. Bioorganic & Medicinal Chemistry Letters
Reilly SW, Riad AA, Hsieh CJ, et al. (2019) Leveraging a Low Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D3 Receptor (D3R) Ligand Promiscuity Across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs). Journal of Medicinal Chemistry
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