Deborah A. Ryan, Ph.D.

Affiliations: 
University of Rochester Medical Center, Rochester, NY, United States 
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Parents

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William J. Bowers grad student 2007-2010 Rochester
 (Targeting amyloid-beta in a passive immunotherapeutic approach to disrupt Alzheimer's disease pathogenesis.)
Doug Portman post-doc 2000- Rochester
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Publications

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Ryan DA, Miller RM, Lee K, et al. (2014) Sex, age, and hunger regulate behavioral prioritization through dynamic modulation of chemoreceptor expression. Current Biology : Cb. 24: 2509-17
Platt B, Drever B, Koss D, et al. (2011) Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1. Plos One. 6: e27068
Ryan DA, Mastrangelo MA, Narrow WC, et al. (2010) Aβ-directed Single-chain Antibody Delivery Via a Serotype-1 AAV Vector Improves Learning Behavior and Pathology in Alzheimer's Disease Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1471-1481
Desai MK, Mastrangelo MA, Ryan DA, et al. (2010) Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target. The American Journal of Pathology. 177: 1422-35
Ryan DA, Mastrangelo MA, Narrow WC, et al. (2010) Abeta-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1471-81
Ryan DA, Narrow WC, Federoff HJ, et al. (2010) An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies. Journal of Neuroscience Methods. 190: 171-9
Bowers WJ, Desai MK, Mastrangelo MA, et al. (2010) P2-242: Oligodendrocyte cell lineage represents an amyloid beta 1-42 sensitive cell population leading to white matter alterations during early Alzheimer's disease Alzheimer's & Dementia. 6: S385-S385
Ryan DA, Federoff HJ. (2009) Immune responses to herpesviral vectors. Human Gene Therapy. 20: 434-41
Chiu YG, Bowers WJ, Lim ST, et al. (2009) Effects of herpes simplex virus amplicon transduction on murine dendritic cells. Human Gene Therapy. 20: 442-52
Federoff HJ, Chiu YG, Bowers WJ, et al. (2009) Effects of HSV amplicon transduction on murine dendritic cells Human Gene Therapy. 90126111624022
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