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Fred W. Keeley

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Biochemistry
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"Fred Keeley"
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Children

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Catherine M. Bellingham grad student 2001 University of Toronto
Yin C. Hew grad student 2001 University of Toronto
Woon-Kai Low grad student 2002 University of Toronto

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Publications

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Reichheld SE, Muiznieks LD, Lu R, et al. (2019) Sequence variants of human tropoelastin affecting assembly, structural characteristics and functional properties of polymeric elastin in health and disease. Matrix Biology : Journal of the International Society For Matrix Biology
Srivastava A, Xue Z, Muiznieks LD, et al. (2019) Solvent Effects on the Self-Assembly and Mechanical Properties of Elastin-Like Peptides Biophysical Journal. 116: 202a
Muiznieks LD, Sharpe S, Pomès R, et al. (2018) Role of Liquid-Liquid Phase Separation in Assembly of Elastin and Other Extracellular Matrix Proteins. Journal of Molecular Biology
Reichheld SE, Muiznieks LD, Keeley FW, et al. (2017) Direct observation of structure and dynamics during phase separation of an elastomeric protein. Proceedings of the National Academy of Sciences of the United States of America
Muiznieks LD, Keeley FW, Pomès R. (2017) Controlling the Biophysical Properties and Functionality of Phase-Separated Elastin-Based Droplets through Amino Acid Sequence Mutations Biophysical Journal. 112: 480a-481a
Miao M, Reichheld SE, Muiznieks LD, et al. (2016) Single Nucleotide Polymorphisms and Domain/Splice Variants Modulate Assembly and Elastomeric Properties of Human Elastin. Implications for Tissue Specificity and Durability of Elastic Tissue. Biopolymers
Muiznieks LD, Keeley FW. (2016) Phase separation and mechanical properties of an elastomeric biomaterial from spider wrapping silk and elastin block copolymers. Biopolymers
Muiznieks LD, Miao M, Sitarz EE, et al. (2016) Contribution of domain 30 of tropoelastin to elastic fiber formation and material elasticity. Biopolymers. 105: 267-75
Muiznieks LD, Keeley FW. (2016) Biomechanical Design of Elastic Protein Biomaterials: A Balance of Protein Structure and Conformational Disorder Acs Biomaterials Science & Engineering. 3: 661-679
Muiznieks LD, Reichheld SE, Sitarz EE, et al. (2015) Proline-poor hydrophobic domains modulate the assembly and material properties of polymeric elastin. Biopolymers. 103: 563-73
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