John D. Crispino

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Molecular Biology, Biochemistry
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Parents

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Phillip Allen Sharp grad student
Stuart H. Orkin post-doc (Neurotree)

Children

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Rahul S. Bhansali grad student (Cell Biology Tree)
Yanfei Xu grad student 2005 Chicago
Cindy G. Leung grad student 2006 Chicago
Andrew G. Muntean grad student 2006 Chicago
Gina T. Kirsammer grad student 2007 Chicago
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Publications

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Jin Q, Gutierrez Diaz B, Pieters T, et al. (2022) Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia. Science Advances. 8: eabq8437
Zhao X, Bartholdy B, Yamamoto Y, et al. (2022) PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development. Communications Biology. 5: 961
Rammohan M, Harris E, Bhansali RS, et al. (2022) The chromosome 21 kinase DYRK1A: emerging roles in cancer biology and potential as a therapeutic target. Oncogene
Bhansali RS, Rammohan M, Lee P, et al. (2021) DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3. The Journal of Clinical Investigation. 131
Schieber M, Marinaccio C, Bolanos LC, et al. (2020) FBXO11 is a candidate tumor suppressor in the leukemic transformation of myelodysplastic syndrome. Blood Cancer Journal. 10: 98
Fang C, Rao S, Crispino JD, et al. (2020) Determinants and role of chromatin organization in acute leukemia. Leukemia
Laurent AP, Siret A, Ignacimouttou C, et al. (2020) Constitutive activation of RAS/MAPK pathway cooperates with trisomy 21 and is therapeutically exploitable in Down syndrome B-cell leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Fruit C, Couly F, Bhansali R, et al. (2019) Biological Characterization of 8-Cyclopropyl-2-(pyridin-3-yl)thiazolo[5,4-]quinazolin-9(8)-one, a Promising Inhibitor of DYRK1A. Pharmaceuticals (Basel, Switzerland). 12
Strouboulis J, Crispino JD. (2019) Preface to IUBMB life special issue on GATA transcription factors in development, differentiation, and disease. Iubmb Life
Ling T, Crispino JD. (2019) GATA1 mutations in red cell disorders. Iubmb Life
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