David M. Ferguson

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biochemistry
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Mahadevan Seetharaman grad student 2003 UMN
Erik C. Jorvig grad student 2004 UMN
John R. Goodell grad student 2006 UMN
Adam R. Benoit grad student 2013 UMN
Mu Yang post-doc 2020- UMN
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Publications

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Liao EE, Yang M, Nathan Kochen N, et al. (2023) Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology. Molecular Neurobiology
Vunnam N, Yang M, Lo CH, et al. (2023) Zafirlukast Is a Promising Scaffold for Selectively Inhibiting TNFR1 Signaling. Acs Bio & Med Chem Au. 3: 270-282
Yang M, Larson PG, Brown L, et al. (2022) Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs. Bioorganic & Medicinal Chemistry Letters. 59: 128548
Kim H, Khanna V, Kucaba TA, et al. (2020) TLR7/8 Agonist Loaded Nanoparticles Augment NK Cell-mediated Antibody-based Cancer Immunotherapy. Molecular Pharmaceutics
Wang X, Zeng Y, Sheng L, et al. (2019) A Cinchona Alkaloid Antibiotic that Appears to Target ATP Synthase in Streptococcus pneumoniae. Journal of Medicinal Chemistry
Bockman MR, Engelhart CA, Cramer JD, et al. (2019) Investigation of (S)-(-)-acidomycin: A selective antimycobacterial natural product that inhibits biotin synthase. Acs Infectious Diseases
Khanna V, Kim H, Zhang W, et al. (2019) Abstract 4129: Novel small molecule TLR7/8 agonists for enhancing NK cell-mediated ADCC Cancer Research. 79: 4129-4129
Larson P, Kucaba TA, Xiong Z, et al. (2017) Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8. Acs Medicinal Chemistry Letters. 8: 1148-1152
Benoit AR, Schiaffo C, Salomon CE, et al. (2014) Synthesis and evaluation of N-alkyl-9-aminoacridines with antibacterial activity. Bioorganic & Medicinal Chemistry Letters. 24: 3014-7
Schiaffo CE, Shi C, Xiong Z, et al. (2014) Structure-activity relationship analysis of imidazoquinolines with Toll-like receptors 7 and 8 selectivity and enhanced cytokine induction. Journal of Medicinal Chemistry. 57: 339-47
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