Guilian Xu, Ph.D.

Neuroscience University of Florida, Gainesville, Gainesville, FL, United States 
transgenic mice, Alzheimer's disease, ALS,
"Guilian Xu"
Mean distance: 16.48 (cluster 31)
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De Rossi P, Andrew RJ, Musial TF, et al. (2018) Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models. Brain Pathology (Zurich, Switzerland)
Pace MC, Xu G, Fromholt S, et al. (2018) Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease. Acta Neuropathologica
Pace MC, Xu G, Fromholt S, et al. (2018) Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology. Molecular Neurodegeneration. 13: 23
Iradi MCG, Triplett JC, Thomas JD, et al. (2018) Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy. Scientific Reports. 8: 4049
Xu G, Pattamatta A, Hildago R, et al. (2016) Vulnerability of newly synthesized proteins to proteostasis stress. Journal of Cell Science. 129: 1892-901
Xu G, Ran Y, Fromholt SE, et al. (2015) Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits. Acta Neuropathologica Communications. 3: 72
Janus C, Flores AY, Xu G, et al. (2015) Behavioral abnormalities in APPSwe/PS1dE9 mouse model of AD-like pathology: comparative analysis across multiple behavioral domains. Neurobiology of Aging. 36: 2519-32
Li Z, Gu TP, Weber AR, et al. (2015) Gadd45a promotes DNA demethylation through TDG. Nucleic Acids Research. 43: 3986-97
Xu G, Fromholt S, Ayers JI, et al. (2015) Substantially elevating the levels of αB-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation. Journal of Neurochemistry. 133: 452-64
Xu G, Ayers JI, Roberts BL, et al. (2015) Direct and indirect mechanisms for wild-type SOD1 to enhance the toxicity of mutant SOD1 in bigenic transgenic mice. Human Molecular Genetics. 24: 1019-35
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