Andrew T. Tebbenkamp, Ph.D.
Affiliations: | Neurobiology | Yale University, New Haven, CT |
Area:
neuroscience, geneticsGoogle:
"Andrew Tebbenkamp"Mean distance: 15.05 (cluster 31) | S | N | B | C | P |
Parents
Sign in to add mentor| David R. Borchelt | grad student | 2005-2010 | UF Gainesville | |
| (Characterization of in vitro and in vivo huntingtin proteolysis in Huntington's disease.) | ||||
| Nenad Sestan | post-doc | 2010- | Yale | |
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Publications
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| Onorati M, Li Z, Liu F, et al. (2016) Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia. Cell Reports |
| Cotney J, Muhle RA, Sanders SJ, et al. (2015) The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment. Nature Communications. 6: 6404 |
| Tebbenkamp AT, Xu G, Siemienski ZB, et al. (2014) Experimental mutagenesis of huntingtin to map cleavage sites: different outcomes in cell and mouse models. Journal of Huntington's Disease. 3: 73-86 |
| Tebbenkamp AT, Willsey AJ, State MW, et al. (2014) The developmental transcriptome of the human brain: implications for neurodevelopmental disorders. Current Opinion in Neurology. 27: 149-56 |
| Willsey AJ, Sanders SJ, Li M, et al. (2013) Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell. 155: 997-1007 |
| Tebbenkamp AT, Crosby KW, Siemienski ZB, et al. (2012) Analysis of proteolytic processes and enzymatic activities in the generation of huntingtin n-terminal fragments in an HEK293 cell model. Plos One. 7: e50750 |
| Tebbenkamp AT, Green C, Xu G, et al. (2011) Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative. Human Molecular Genetics. 20: 2770-82 |
| Tebbenkamp AT, Swing D, Tessarollo L, et al. (2011) Premature death and neurologic abnormalities in transgenic mice expressing a mutant huntingtin exon-2 fragment. Human Molecular Genetics. 20: 1633-42 |
| Tebbenkamp AT, Borchelt DR. (2010) Analysis of chaperone mRNA expression in the adult mouse brain by meta analysis of the Allen Brain Atlas. Plos One. 5: e13675 |
| Klevytska AM, Tebbenkamp AT, Savonenko AV, et al. (2010) Partial depletion of CREB-binding protein reduces life expectancy in a mouse model of Huntington disease. Journal of Neuropathology and Experimental Neurology. 69: 396-404 |