Lee Limbird
Affiliations: | 1979- | Pharmacology | Vanderbilt University, Nashville, TN |
Website:
https://medschool.vanderbilt.edu/pharmacology/person/lee-limbirdGoogle:
"Lee Limbird"Bio:
https://books.google.com/books?id=bwsoAQAAIAAJ
Mean distance: 13.64 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Karl Hermann Friedrich Blau | grad student | 1973 | UNC Chapel Hill (Chemistry Tree) | |
| (Development of a method for the detection and quantitation of the isoenzymes of creatine phosphokinase and the application of combined creatine phosphokinase and lactate dehydrogenase issoenzyme analysis to the recognition of acute myocardial infarction.) | ||||
| Robert J. Lefkowitz | post-doc | 1973-1978 | Duke | |
Children
Sign in to add trainee| Thomas M. Connolly | grad student | 1983 | Vanderbilt |
| J. David Sweatt | grad student | 1982-1986 | Vanderbilt |
| Jodi Marie Nunnari | grad student | 1989 | Vanderbilt (Cell Biology Tree) |
| David J. Clark | grad student | 1990 | Vanderbilt |
| Brian P. Ceresa | grad student | 1995 | Vanderbilt (Cell Biology Tree) |
| Nicole L. Schramm | grad student | 2000 | Vanderbilt |
| Ashley E. Brady | grad student | 2003 | Vanderbilt |
| Hilary A. Highfield (Nickols) | grad student | 2004 | Vanderbilt |
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Publications
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| Ding Q, Chorazyczewski J, Gros R, et al. (2022) Correlation of functional and radioligand binding characteristics of GPER ligands confirming aldosterone as a GPER agonist. Pharmacology Research & Perspectives. 10: e00995 |
| Feldman RD, Limbird LE. (2015) Copernicus Revisited: Overturning Ptolemy's View of the GPER Universe. Trends in Endocrinology and Metabolism: Tem. 26: 592-4 |
| Limbird LE. (2011) Historical perspective for understanding of adrenergic receptors. Current Topics in Membranes. 67: 1-17 |
| Brady AE, Chen Y, Limbird LE, et al. (2011) Study of GPCR-protein interactions using gel overlay assays and glutathione-S-transferase-fusion protein pull-downs. Methods in Molecular Biology (Clifton, N.J.). 746: 347-55 |
| Lu R, Chen Y, Cottingham C, et al. (2010) Enhanced hypotensive, bradycardic, and hypnotic responses to alpha2-adrenergic agonists in spinophilin-null mice are accompanied by increased G protein coupling to the alpha2A-adrenergic receptor. Molecular Pharmacology. 78: 279-86 |
| Lu R, Li Y, Zhang Y, et al. (2009) Epitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalization. The Journal of Biological Chemistry. 284: 13233-43 |
| Mines MA, Goodwin JS, Limbird LE, et al. (2009) Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation. The Journal of Biological Chemistry. 284: 5742-52 |
| Nag S, Wang Q, Limbird LE, et al. (2009) Knockout of spinophilin, an endogenous antagonist of arrestin-dependent alpha2-adrenoceptor functions, enhances receptor-mediated antinociception yet does not eliminate sex-related differences. Behavioural Brain Research. 197: 457-61 |
| Wang Q, Limbird LE. (2007) Regulation of alpha2AR trafficking and signaling by interacting proteins. Biochemical Pharmacology. 73: 1135-45 |
| Wang Q, Lu R, Zhao J, et al. (2006) Arrestin serves as a molecular switch, linking endogenous alpha2-adrenergic receptor to SRC-dependent, but not SRC-independent, ERK activation. The Journal of Biological Chemistry. 281: 25948-55 |