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Rory D. Spence, Ph.D.

Affiliations: 
2013 Neuroscience 004F University of California, Los Angeles, Los Angeles, CA 
Area:
Neuroscience Biology, Immunology
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"Rory Spence"
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Parents

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Barney A. Schlinger grad student UCLA
Rhonda R. Voskuhl grad student 2013 UCLA
 (Estrogen Signaling through Estrogen Receptor Alpha in Astrocytes Mediates Neuroprotection during Experimental Autoimmune Encephalomyelitis and Decreases Astrocyte Levels of Proinflammatory Chemokines.)

Children

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Amanda L Maheras research assistant 2016-2017 Claremont McKenna, Pitzer, and Scripps Colleges

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Publications

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Maheras AL, Dix B, Carmo OMS, et al. (2018) Genetic Pathways of Neuroregeneration in a Novel Mild Traumatic Brain Injury Model in Adult Zebrafish. Eneuro. 5
Spence RD, Kurth F, Itoh N, et al. (2014) Bringing CLARITY to gray matter atrophy. Neuroimage. 101: 625-32
Kim RY, Hoffman AS, Itoh N, et al. (2014) Astrocyte CCL2 sustains immune cell infiltration in chronic experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 274: 53-61
Spence RD, Wisdom AJ, Cao Y, et al. (2013) Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ERα signaling on astrocytes but not through ERβ signaling on astrocytes or neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10924-33
Wisdom AJ, Cao Y, Itoh N, et al. (2013) Estrogen receptor-β ligand treatment after disease onset is neuroprotective in the multiple sclerosis model. Journal of Neuroscience Research. 91: 901-8
Gold SM, Sasidhar MV, Lagishetty V, et al. (2012) Dynamic development of glucocorticoid resistance during autoimmune neuroinflammation. The Journal of Clinical Endocrinology and Metabolism. 97: E1402-10
Spence RD, Voskuhl RR. (2012) Neuroprotective effects of estrogens and androgens in CNS inflammation and neurodegeneration. Frontiers in Neuroendocrinology. 33: 105-15
Gold S, Sasidhar M, Lagishetty V, et al. (2012) Modulation of glucocorticoid sensitivity in T cells: A novel mechanism for the beneficial effects of pregnancy in multiple sclerosis Journal of Reproductive Immunology. 94: 33-34
Spence RD, Hamby ME, Umeda E, et al. (2011) Neuroprotection mediated through estrogen receptor-alpha in astrocytes. Proceedings of the National Academy of Sciences of the United States of America. 108: 8867-72
Mirzatoni A, Spence RD, Naranjo KC, et al. (2010) Injury-induced regulation of steroidogenic gene expression in the cerebellum. Journal of Neurotrauma. 27: 1875-82
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