Rana Rais, Ph.D.
Affiliations: | 2010 | Pharmaceutical Sciences | University of Maryland School of Medicine, Baltimore, MD, United States |
Area:
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"Rana Rais"Parents
Sign in to add mentor| James E. Polli | grad student | 2010 | University of Maryland Medical School | |
| (Delineating structural requirements of hASBT: A rational approach to prodrug design.) | ||||
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Publications
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| Duvall B, Zimmermann SC, Gao RD, et al. (2020) Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker. Bioorganic & Medicinal Chemistry. 28: 115698 |
| Giancola JB, Bonifazi A, Cao J, et al. (2020) Structure-activity relationships for a series of (Bis(4-fluorophenyl)methyl)sulfinylethyl-aminopiperidines and -piperidine amines at the dopamine transporter: Bioisosteric replacement of the piperazine improves metabolic stability. European Journal of Medicinal Chemistry. 208: 112674 |
| Khoury ES, Sharma A, Ramireddy RR, et al. (2020) Dendrimer-conjugated glutaminase inhibitor selectively targets microglial glutaminase in a mouse model of Rett syndrome. Theranostics. 10: 5736-5748 |
| Oh MH, Sun IH, Zhao L, et al. (2020) Targeting glutamine metabolism enhances tumor specific immunity by modulating suppressive myeloid cells. The Journal of Clinical Investigation |
| Sala M, Hollinger KR, Thomas AG, et al. (2020) Novel human neutral sphingomyelinase 2 inhibitors as potential therapeutics for Alzheimer disease. Journal of Medicinal Chemistry |
| Powell J, Leone R, Oh M, et al. (2020) Abstract IA10: Targeting glutamine metabolism as a means of enhancing immunotherapy for cancer Clinical Cancer Research. 26 |
| Leone RD, Zhao L, Englert JM, et al. (2019) Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science (New York, N.Y.) |
| Slack RD, Ku T, Cao J, et al. (2019) Structure-Activity Relationships for a series of bis(4-fluorophenyl)methyl)sulfinyl)alkyl alicyclic amines at the dopamine transporter: functionalizing the terminal nitrogen affects affinity, selectivity and metabolic stability. Journal of Medicinal Chemistry |
| Lemberg KM, Zhao L, Wu Y, et al. (2019) The novel glutamine antagonist prodrug JHU395 has antitumor activity in malignant peripheral nerve sheath tumor. Molecular Cancer Therapeutics |
| Shaik AB, Kumar V, Bonifazi A, et al. (2019) Investigation of novel primary and secondary pharmacophores, and 3-substitution in the linking chain of a series of highly selective and bitopic dopamine D3 receptor antagonists and partial agonists. Journal of Medicinal Chemistry |