Melissa N. Holowaty, Ph.D.

Affiliations: 
2004 University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology
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"Melissa Holowaty"

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Lori Frappier grad student 2004 University of Toronto
 (Identification of cellular protein interactions with the EBNA1 protein of Epstein -Barr virus and characterization of the interaction with USP7.)
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Sarkari F, Sanchez-Alcaraz T, Wang S, et al. (2009) EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication. Plos Pathogens. 5: e1000624
Saridakis V, Sheng Y, Sarkari F, et al. (2005) Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Molecular Cell. 18: 25-36
Holowaty MN, Frappier L. (2004) HAUSP/USP7 as an Epstein-Barr virus target. Biochemical Society Transactions. 32: 731-2
Holowaty MN, Sheng Y, Nguyen T, et al. (2003) Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP. The Journal of Biological Chemistry. 278: 47753-61
Holowaty MN, Zeghouf M, Wu H, et al. (2003) Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7. The Journal of Biological Chemistry. 278: 29987-94
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