Thomas J. Hannan, Ph.D.

Affiliations: 
2008 Washington University, Saint Louis, St. Louis, MO 
Area:
Microbiology Biology, Immunology, Pathology
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"Thomas Hannan"

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Scott J. Hultgren grad student 2008 Washington University
 (Early events in mucosal infection by uropathogenic Escherichia coli.)
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Publications

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Rosen AL, Lint MA, Voelker DH, et al. (2024) Secretory leukocyte protease inhibitor protects against severe urinary tract infection in mice. Mbio. e0255423
Rosen AL, Lint MA, Voelker DH, et al. (2023) Secretory Leukocyte Protease Inhibitor Protects Against Severe Urinary Tract Infection in Mice. Biorxiv : the Preprint Server For Biology
Russell SK, Harrison JK, Olson BS, et al. (2023) Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome. Nature Microbiology
Worby CJ, Schreiber HL, Straub TJ, et al. (2022) Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women. Nature Microbiology. 7: 630-639
Yu L, O'Brien VP, Livny J, et al. (2019) Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence. Elife. 8
Yu L, O'Brien VP, Livny J, et al. (2019) Author response: Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence Elife
O'Brien VP, Dorsey DA, Hannan TJ, et al. (2018) Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner. Plos Pathogens. 14: e1007457
Mydock-McGrane LK, Hannan TJ, Janetka JW. (2017) Rational Design Strategies for FimH Antagonists: New Drugs on the Horizon for Urinary Tract Infection and Crohn's Disease. Expert Opinion On Drug Discovery
Schreiber HL, Conover MS, Chou WC, et al. (2017) Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections. Science Translational Medicine. 9
Kalas V, Pinkner JS, Hannan TJ, et al. (2017) Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions. Science Advances. 3: e1601944
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