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Elizabeth A. Pehek

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Serotonin-2 Receptors and Mesocortical Dopamine: Neural Circuitry
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"Elizabeth Pehek"
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Parents

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Elaine M. Hull grad student 1982-1988 State University of New York at Buffalo

Children

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Amanda E. Hernan research assistant 2005-2007 Case Western
Aphroditi (Didi) Mamaligas research assistant 2010-2011
Hewlet McFarlane grad student 2000-2001 Case Western Medical School
Sara Gerke post-doc Case Western Medical School
Christine Nocjar post-doc 1998-2001 Case Western Medical School

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Publications

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Nocjar C, Alex KD, Sonneborn A, et al. (2015) Serotonin-2C and -2a receptor co-expression on cells in the rat medial prefrontal cortex. Neuroscience. 297: 22-37
Pehek EA, Hernan AE. (2015) Stimulation of glutamate receptors in the ventral tegmental area is necessary for serotonin-2 receptor-induced increases in mesocortical dopamine release. Neuroscience. 290: 159-64
Burke MV, Nocjar C, Sonneborn AJ, et al. (2014) Striatal serotonin 2C receptors decrease nigrostriatal dopamine release by increasing GABA-A receptor tone in the substantia nigra. Journal of Neurochemistry. 131: 432-43
Golden JP, Demaro JA, Knoten A, et al. (2013) Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17095-107
Yao C, El Khoury R, Wang W, et al. (2010) LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease. Neurobiology of Disease. 40: 73-81
Cao P, Yuan Y, Pehek EA, et al. (2010) Alpha-synuclein disrupted dopamine homeostasis leads to dopaminergic neuron degeneration in Caenorhabditis elegans. Plos One. 5: e9312
Gallitano-Mendel A, Wozniak DF, Pehek EA, et al. (2008) Mice lacking the immediate early gene Egr3 respond to the anti-aggressive effects of clozapine yet are relatively resistant to its sedating effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1266-75
Alex KD, Pehek EA. (2007) Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission. Pharmacology & Therapeutics. 113: 296-320
Jain S, Golden JP, Wozniak D, et al. (2006) RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11230-8
Pehek EA, Nocjar C, Roth BL, et al. (2006) Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 265-77
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