Douglas L. Rothman
Affiliations: | Diagnostic Radiology | Yale University, New Haven, CT |
Area:
Development of magnetic resonance spectroscopy and magnetic resonance imaging methods to image metabolic and neurotransmitter pathways non-invasively in humans and in animal models.Website:
http://seas.yale.edu/faculty-research/faculty-directory/douglas-l-rothmanGoogle:
"Douglas Rothman"Bio:
http://scholar.google.com/citations?user=18-0e2EAAAAJ&hl=en
http://proquest.umi.com/pqdlink?did=753399141&Fmt=7&clientId =79356&RQT=309&VName=PQD
Mean distance: 15.72 (cluster 51) | S | N | B | C | P |
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Robert G. Shulman | grad student | 1987 | Yale | |
| (Application of Multipulse ¹H and ¹³C NMR for Measuring in vivo rates of Metabolism) | ||||
Children
Sign in to add trainee| Jason Tucciarone | research assistant | Yale School of Medicine | |
| James R. Schafer | grad student | 2006 | Yale |
| Kevin M. Koch | grad student | 2007 | Yale |
| D. S. Fahmeed Hyder | post-doc | Yale |
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Publications
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| Rothman DL, Moore PB, Shulman RG. (2023) The impact of metabolism on the adaptation of organisms to environmental change. Frontiers in Cell and Developmental Biology. 11: 1197226 |
| DiNuzzo M, Dienel GA, Behar KL, et al. (2023) Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCO and pO. Journal of Neurochemistry |
| Chowdhury GMI, Behar KL, Mason GF, et al. (2023) Measurement of neuro-energetics and neurotransmission in the rat olfactory bulb using H and H-[ C] NMR spectroscopy. Nmr in Biomedicine. e4957 |
| Rothman D, Behar KL, Petroff OAC, et al. (2022) The early days of ex vivo H, C and P NMR in the laboratory of Dr. Robert G Shulman from 1975 - 1995. Nmr in Biomedicine. e4879 |
| Rothman DL, Behar KL, Dienel GA. (2022) Mechanistic stoichiometric relationship between the rates of neurotransmission and neuronal glucose oxidation: Reevaluation of and alternatives to the pseudo-malate-aspartate shuttle model. Journal of Neurochemistry |
| Averill LA, Jiang L, Purohit P, et al. (2022) Prefrontal Glutamate Neurotransmission in PTSD: A Novel Approach to Estimate Synaptic Strength in Vivo in Humans. Chronic Stress (Thousand Oaks, Calif.). 6: 24705470221092734 |
| Sanchez-Rangel E, Gunawan F, Jiang L, et al. (2022) Reversibility of brain glucose kinetics in type 2 diabetes mellitus. Diabetologia |
| Koush Y, Rothman DL, Behar KL, et al. (2022) Human brain functional MRS reveals interplay of metabolites implicated in neurotransmission and neuroenergetics. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X221076570 |
| McNair LM, Mason GF, Chowdhury GM, et al. (2022) Rates of pyruvate carboxylase, glutamate and GABA neurotransmitter cycling, and glucose oxidation in multiple brain regions of the awake rat using a combination of [2-C]/[1-C]glucose infusion and H-[C]NMR . Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X221074211 |
| Rothman DL, Dienel GA, Behar KL, et al. (2022) Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211064399 |