Robert Karoly, Ph.D.

Affiliations: 
2010 Semmelweis Egyetem, Hungary 
Area:
Neuroscience Biology
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"Robert Karoly"
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Mike Arpad grad student 2010 Semmelweis Egyetem
 (Kinetikai modellezes alkalmazasa a gyogyszerkutatasban.)
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Publications

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Lenkey N, Karoly R, Epresi N, et al. (2011) Binding of sodium channel inhibitors to hyperpolarized and depolarized conformations of the channel Neuropharmacology. 60: 191-200
Lenkey N, Karoly R, Lukacs P, et al. (2010) Classification of drugs based on properties of sodium channel inhibition: a comparative automated patch-clamp study. Plos One. 5: e15568
McCormack TJ, Melis C, Colón J, et al. (2010) Rapid desensitization of the rat α7 nAChR is facilitated by the presence of a proline residue in the outer β-sheet. The Journal of Physiology. 588: 4415-29
Karoly R, Lenkey N, Juhasz AO, et al. (2010) Fast- or slow-inactivated state preference of Na+ channel inhibitors: a simulation and experimental study. Plos Computational Biology. 6: e1000818
Szasz BK, Mike A, Karoly R, et al. (2007) Direct inhibitory effect of fluoxetine on N-methyl-D-aspartate receptors in the central nervous system. Biological Psychiatry. 62: 1303-9
Lenkey N, Karoly R, Kiss JP, et al. (2006) The mechanism of activity-dependent sodium channel inhibition by the antidepressants fluoxetine and desipramine. Molecular Pharmacology. 70: 2052-63
Karoly R, Lenkey N, Mike A, et al. (2006) Modelling drug effects on sodium channels Autonomic and Autacoid Pharmacology. 26: 91
Mike A, Karoly R, Vizi ES, et al. (2003) Inhibitory effect of the DA uptake blocker GBR 12909 on sodium channels of hippocampal neurons. Neuroreport. 14: 1945-9
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