Justin M. Long, Ph.D.

Affiliations: 
2013 Medical Neurobiology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Neuroscience Biology, Molecular Biology
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"Justin Long"
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Parents

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Debomoy K. Lahiri grad student 2013 Indiana University
 (Novel regulation of neuronal genes implicated in Alzheimer disease by microRNA.)
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Publications

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Toral-Rios D, Long JM, Ulrich JD, et al. (2024) Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy. The Journal of Experimental Medicine. 221
Shi Y, Manis M, Long J, et al. (2019) Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model. The Journal of Experimental Medicine
Long JM, Holtzman DM. (2019) Alzheimer Disease: An Update on Pathobiology and Treatment Strategies. Cell. 179: 312-339
Long JM, Maloney B, Rogers JT, et al. (2018) Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5'-untranslated region: Implications in Alzheimer's disease. Molecular Psychiatry
Lahiri DK, Maloney B, Long J, et al. (2015) P2-048: Does the mini-mental state examination (MMSE) measure a deeper biological process? modeling mmse score versus three selected mirna levels may reveal pathological roles in Alzheimer's disease progression Alzheimer's & Dementia. 11: P499-P500
Ray B, Chopra N, Long JM, et al. (2014) Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research. Molecular Brain. 7: 63
Lahiri DK, Maloney B, Long JM, et al. (2014) Lessons from a BACE1 inhibitor trial: off-site but not off base. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S411-9
Long JM, Ray B, Lahiri DK. (2014) MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects. The Journal of Biological Chemistry. 289: 5184-98
Lahiri DK, Long JM. (2014) P4-219: MICRORNA-339-5P IS DYSREGULATED IN ALZHEIMER'S DISEASE AND IS INVERSELY PROPORTIONAL TO BACE1 EXPRESSION: IMPLICATION IN TESTING NOVEL DRUG TARGETS Alzheimer's & Dementia. 10: P868-P868
Lahiri D, Long J, Chopra N, et al. (2013) O5-06-02: MicroRNA-346 stimulates APP expression by blockading an iron response element in the APP 5'-UTR: A novel therapeutic target for Alzheimer's disease (AD) Alzheimer's & Dementia. 9: P839-P839
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