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Olga Y. Lubman, Ph.D.

Affiliations: 
2002 Washington University, Saint Louis, St. Louis, MO 
Area:
Medical Biophysics
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"Olga Lubman"
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Gabriel Waksman grad student 2002 Washington University
 (Structural and thermodynamic investigation of Src SH2 domain recognition.)

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Lubman OY, Fremont DH. (2016) Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors. Structure (London, England : 1993). 24: 57-69
Lubman OY, Cella M, Wang X, et al. (2014) Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor. Journal of Virology. 88: 538-46
Tomasson MH, Xiang Z, Walgren R, et al. (2008) Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood. 111: 4797-808
Lubman OY, Ilagan MX, Kopan R, et al. (2007) Quantitative dissection of the Notch:CSL interaction: insights into the Notch-mediated transcriptional switch. Journal of Molecular Biology. 365: 577-89
Lubman OY, Kopan R, Waksman G, et al. (2005) The crystal structure of a partial mouse Notch-1 ankyrin domain: repeats 4 through 7 preserve an ankyrin fold. Protein Science : a Publication of the Protein Society. 14: 1274-81
Lubman OY, Korolev SV, Kopan R. (2004) Anchoring notch genetics and biochemistry; structural analysis of the ankyrin domain sheds light on existing data. Molecular Cell. 13: 619-26
Waksman G, Kumaran S, Lubman O. (2004) SH2 domains: role, structure and implications for molecular medicine. Expert Reviews in Molecular Medicine. 6: 1-18
Lubman OY, Waksman G. (2003) Structural and thermodynamic basis for the interaction of the Src SH2 domain with the activated form of the PDGF beta-receptor. Journal of Molecular Biology. 328: 655-68
Lubman OY, Waksman G. (2002) Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface. Journal of Molecular Biology. 316: 291-304
Davidson JP, Lubman O, Rose T, et al. (2002) Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding. Journal of the American Chemical Society. 124: 205-15
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