Jennifer M. Harrell, Ph.D.
Affiliations: | 2004 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
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Parents
Sign in to add mentor| William B. Pratt | grad student | 2004 | University of Michigan | |
| (Interactions of the hsp90-binding immunophilins and the dynein retrograde motor system.) | ||||
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Publications
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| Thomas M, Harrell JM, Morishima Y, et al. (2006) Pharmacologic and genetic inhibition of hsp90-dependent trafficking reduces aggregation and promotes degradation of the expanded glutamine androgen receptor without stress protein induction. Human Molecular Genetics. 15: 1876-83 |
| Harrell JM, Murphy PJ, Morishima Y, et al. (2004) Evidence for glucocorticoid receptor transport on microtubules by dynein. The Journal of Biological Chemistry. 279: 54647-54 |
| Pratt WB, Galigniana MD, Harrell JM, et al. (2004) Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement. Cellular Signalling. 16: 857-72 |
| Gerges NZ, Tran IC, Backos DS, et al. (2004) Independent functions of hsp90 in neurotransmitter release and in the continuous synaptic cycling of AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4758-66 |
| Murphy PJ, Galigniana MD, Morishima Y, et al. (2004) Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation. The Journal of Biological Chemistry. 279: 30195-201 |
| Galigniana MD, Harrell JM, Housley PR, et al. (2004) Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation. Brain Research. Molecular Brain Research. 123: 27-36 |
| Galigniana MD, Harrell JM, O'Hagen HM, et al. (2004) Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus. The Journal of Biological Chemistry. 279: 22483-9 |
| Thomas M, Dadgar N, Aphale A, et al. (2004) Androgen receptor acetylation site mutations cause trafficking defects, misfolding, and aggregation similar to expanded glutamine tracts. The Journal of Biological Chemistry. 279: 8389-95 |
| Zheng J, Yang X, Harrell JM, et al. (2002) CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex. Molecular Cell. 10: 1519-26 |
| Galigniana MD, Harrell JM, Murphy PJ, et al. (2002) Binding of hsp90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain. Biochemistry. 41: 13602-10 |