Zachary R. Healy, Ph.D.

Affiliations: 
2007 Johns Hopkins University, Baltimore, MD 
Area:
Chemical Engineering
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Konstantinos Konstantopoulos grad student 2007 Johns Hopkins
 (The effects of fluid shear stress on pro- and anti -inflammatory signaling in chondrocytes: Cross-talk among COX -2, the phase 2 response, and apoptosis.)
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Publications

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Healy ZR, Weinhold KJ, Murdoch DM. (2020) Transcriptional Profiling of CD8+ CMV-Specific T Cell Functional Subsets Obtained Using a Modified Method for Isolating High-Quality RNA From Fixed and Permeabilized Cells. Frontiers in Immunology. 11: 1859
Dayalan Naidu S, Dikovskaya D, Gaurilcikaite E, et al. (2017) Transcription factors NRF2 and HSF1 have opposing functions in autophagy. Scientific Reports. 7: 11023
Healy ZR, Murdoch DM. (2016) OMIP-036: Co-inhibitory receptor (immune checkpoint) expression analysis in human T cell subsets. Cytometry. Part a : the Journal of the International Society For Analytical Cytology
Healy ZR, Liu H, Holtzclaw WD, et al. (2011) Inactivation of tautomerase activity of macrophage migration inhibitory factor by sulforaphane: A potential biomarker for anti-inflammatory intervention Cancer Epidemiology Biomarkers and Prevention. 20: 1516-1523
Suganuma H, Fahey JW, Bryan KE, et al. (2011) Stimulation of phagocytosis by sulforaphane Biochemical and Biophysical Research Communications. 405: 146-151
Healy ZR, Zhu F, Stull JD, et al. (2008) Elucidation of the signaling network of COX-2 induction in sheared chondrocytes: COX-2 is induced via a Rac/MEKK1/MKK7/JNK2/c-Jun-C/EBPbeta-dependent pathway. American Journal of Physiology. Cell Physiology. 294: C1146-57
Napier SL, Healy ZR, Schnaar RL, et al. (2007) Selectin ligand expression regulates the initial vascular interactions of colon carcinoma cells: the roles of CD44v and alternative sialofucosylated selectin ligands. The Journal of Biological Chemistry. 282: 3433-41
Healy ZR, Lee NH, Gao X, et al. (2005) Divergent responses of chondrocytes and endothelial cells to shear stress: Cross-talk among COX-2, the phase 2 response, and apoptosis Proceedings of the National Academy of Sciences of the United States of America. 102: 14010-14015
Hardesty KJ, Healy ZR, Kensler T, et al. (2005) Identification of shear stress-responsive elements of the cyclooxygenase-2 gene in human chondrocytes Aiche Annual Meeting, Conference Proceedings. 8760
Healy ZR, Lee N, Talalay P, et al. (2005) Elucidation of intracellular signaling pathways in shear-activated chondrocytes: A role in arthritis Aiche Annual Meeting, Conference Proceedings. 8072
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