Shawn C. Little, Ph.D.

Affiliations: 
Molecular Biology Princeton University, Princeton, NJ 
Area:
Developmental Biology
Google:
"Shawn Little"
Mean distance: 14.74 (cluster 57)
 
SNBCP
Cross-listing: FlyTree - Chemistry Tree

Parents

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Mary Mullins grad student 2008 Penn
 (The emergence of embryonic dorsal -ventral pattern through the interactions of BMP ligands with their receptors and modulators.)
Eric F. Wieschaus post-doc 2008- Princeton (FlyTree)
Thomas Gregor post-doc 2009-2016 Princeton (Physics Tree)
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Publications

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Aleman JR, Little SC, Capelson M. (2022) Using Single Molecule RNA FISH to Determine Nuclear Export and Transcription Phenotypes in Drosophila Tissues. Methods in Molecular Biology (Clifton, N.J.). 2502: 113-125
Tajer B, Dutko JA, Little SC, et al. (2021) BMP heterodimers signal via distinct type I receptor class functions. Proceedings of the National Academy of Sciences of the United States of America. 118
Kuhn TM, Pascual-Garcia P, Gozalo A, et al. (2019) Chromatin targeting of nuclear pore proteins induces chromatin decondensation. The Journal of Cell Biology
Chen H, Einstein LC, Little SC, et al. (2019) Spatiotemporal Patterning of Zygotic Genome Activation in a Model Vertebrate Embryo. Developmental Cell. 49: 852-866.e7
Petrovic J, Zhou Y, Fasolino M, et al. (2019) Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques. Molecular Cell
Zoller B, Little SC, Gregor T. (2018) Diverse Spatial Expression Patterns Emerge from Unified Kinetics of Transcriptional Bursting. Cell. 175: 835-847.e25
Little SC, Gregor T. (2018) Single mRNA Molecule Detection in Drosophila. Methods in Molecular Biology (Clifton, N.J.). 1649: 127-142
Little SC, Sinsimer KS, Lee JJ, et al. (2016) Corrigendum: Independent and coordinate trafficking of single Drosophila germ plasm mRNAs. Nature Cell Biology. 18: 347
Tikhonov M, Little SC, Gregor T. (2015) Only accessible information is useful: insights from gradient-mediated patterning. Royal Society Open Science. 2: 150486
Little SC, Sinsimer KS, Lee JJ, et al. (2015) Independent and coordinate trafficking of single Drosophila germ plasm mRNAs. Nature Cell Biology. 17: 558-68
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