George K. Aghajanian

Affiliations: 
Yale University, New Haven, CT 
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"George Aghajanian"
Mean distance: 13.43 (cluster 6)
 
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Publications

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Duman RS, Aghajanian GK, Sanacora G, et al. (2016) Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants. Nature Medicine. 22: 238-49
Fuchikami M, Thomas A, Liu R, et al. (2015) Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions. Proceedings of the National Academy of Sciences of the United States of America. 112: 8106-11
Liu RJ, Ota KT, Dutheil S, et al. (2015) Ketamine Strengthens CRF-Activated Amygdala Inputs to Basal Dendrites in mPFC Layer V Pyramidal Cells in the Prelimbic but not Infralimbic Subregion, A Key Suppressor of Stress Responses. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 2066-75
Ota KT, Liu RJ, Voleti B, et al. (2014) REDD1 is essential for stress-induced synaptic loss and depressive behavior. Nature Medicine. 20: 531-5
Land BB, Narayanan NS, Liu RJ, et al. (2014) Medial prefrontal D1 dopamine neurons control food intake. Nature Neuroscience. 17: 248-53
Duman RS, Aghajanian GK. (2014) Neurobiology of rapid acting antidepressants: role of BDNF and GSK-3β. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 233
Voleti B, Navarria A, Liu RJ, et al. (2013) Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses. Biological Psychiatry. 74: 742-9
Liu RJ, Fuchikami M, Dwyer JM, et al. (2013) GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2268-77
Duman RS, Aghajanian GK. (2012) Synaptic dysfunction in depression: potential therapeutic targets. Science (New York, N.Y.). 338: 68-72
Liu RJ, Lee FS, Li XY, et al. (2012) Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex. Biological Psychiatry. 71: 996-1005
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