Arno L. Greenleaf
Affiliations: | Duke University, Durham, NC |
Area:
BiochemistryGoogle:
"Arno Greenleaf"Bio:
https://news.google.com/?edchanged=1&hl=en-US&gl=US&ceid=US:en
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Parents
Sign in to add mentor| Richard M. Losick | grad student | 1974 | Harvard | |
| (RNA polymerase-binding proteins from sporulating Bacillus subtilis.) | ||||
Children
Sign in to add trainee| David A. Skaar | grad student | 2002 | Duke |
| Hemali P. Phatnani | grad student | 2004 | Duke |
| April L. MacKellar | grad student | 2011 | Duke |
| Tiffany S. Winsor | grad student | 2012 | Duke |
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Publications
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| Magnuson B, Bedi K, Narayanan IV, et al. (2022) CDK12 regulates co-transcriptional splicing and RNA turnover in human cells. Iscience. 25: 105030 |
| Bartkowiak B, Yan CM, Soderblom EJ, et al. (2019) CDK12 Activity-Dependent Phosphorylation Events in Human Cells. Biomolecules. 9 |
| Krajewska M, Dries R, Grassetti AV, et al. (2019) CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation. Nature Communications. 10: 1757 |
| Zhang T, Kwiatkowski N, Olson CM, et al. (2016) Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nature Chemical Biology |
| Bartkowiak B, Yan C, Greenleaf AL. (2015) Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas. Biochimica Et Biophysica Acta. 1849: 1179-87 |
| Bartkowiak B, Greenleaf AL. (2015) Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex. The Journal of Biological Chemistry. 290: 1786-95 |
| Winsor TS, Bartkowiak B, Bennett CB, et al. (2013) A DNA damage response system associated with the phosphoCTD of elongating RNA polymerase II. Plos One. 8: e60909 |
| Liu J, Fan S, Lee CJ, et al. (2013) Specific interaction of the transcription elongation regulator TCERG1 with RNA polymerase II requires simultaneous phosphorylation at Ser2, Ser5, and Ser7 within the carboxyl-terminal domain repeat. The Journal of Biological Chemistry. 288: 10890-901 |
| Möller A, Xie SQ, Hosp F, et al. (2012) Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease. Molecular & Cellular Proteomics : McP. 11: M111.011767 |
| Bartkowiak B, Mackellar AL, Greenleaf AL. (2011) Updating the CTD Story: From Tail to Epic. Genetics Research International. 2011: 623718 |