Klemens Kaupmann

Affiliations: 
Novartis pharma, Basel, Basel, Basel-Stadt, Switzerland 
Area:
GABAB receptors
Google:
"Klemens Kaupmann"
Mean distance: 19.33 (cluster 32)
 
Cross-listing: Chemistry Tree

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Publications

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Alexander SPH, Christopoulos A, Davenport AP, et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British Journal of Pharmacology. S23-S144
Alexander SP, Christopoulos A, Davenport AP, et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. British Journal of Pharmacology. 178: S27-S156
Haffke M, Fehlmann D, Rummel G, et al. (2019) Structural basis of species-selective antagonist binding to the succinate receptor. Nature. 574: 581-585
Bettler B, Bowery NG, Cryan JF, et al. (2019) GABAB receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019
Hoegenauer K, Kallen J, Jiménez-Núñez E, et al. (2019) Structure-based and property-driven optimization of N-aryl imidazoles towards potent and selective oral ROR gamma t inhibitors. Journal of Medicinal Chemistry. 62: 10816-10832
Carcache D, Vulpetti A, Kallen J, et al. (2018) Optimizing a weakly binding fragment into a potent RORγt inverse agonist with efficacy in an in vivo inflammation model. Journal of Medicinal Chemistry
Guendisch U, Weiss J, Ecoeur F, et al. (2017) Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo. Plos One. 12: e0188391
Kallen J, Izaac A, Be C, et al. (2017) Structural states of RORγt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds. Chemmedchem
Guntermann C, Piaia A, Hamel ML, et al. (2017) Retinoic-acid-orphan-receptor-C inhibition suppresses Th17 cells and induces thymic aberrations. Jci Insight. 2: e91127
Jacobson LH, Hoyer D, Fehlmann D, et al. (2017) Blunted 5-HT1A receptor-mediated responses and antidepressant-like behavior in mice lacking the GABAB1a but not GABAB1b subunit isoforms. Psychopharmacology
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