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Rania M. El Sayed, Ph.D.

Affiliations: 
2009 Virginia Commonwealth University, Richmond, VA, United States 
Area:
Immunology, Microbiology Biology
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"Rania El Sayed"
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John G. Tew grad student 2009 VCU
 (Role of FDCs and FDC activation in promoting humoral immunity including responses to T -dependent antigens in the absence of T cells.)

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Publications

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El Shikh M, Biggioggero M, El Sayed R, et al. (2013) OP0218 Regulation of auto-antibody production by auto-immune complexes on follicular dendritic cells Annals of the Rheumatic Diseases. 71: 129.3-129
Tew JG, El Shikh ME, El Sayed RM, et al. (2012) Dendritic cells, antibodies reactive with oxLDL, and inflammation. Journal of Dental Research. 91: 8-16
El Shikh MEM, Biggioggero M, El Sayed RM, et al. (2012) Regulation of auto-antibody production by persisting auto-immune complexes on follicular dendritic cells Annals of the Rheumatic Diseases. 71: A38.1-A38
El Shikh ME, El Sayed RM, Kmieciak M, et al. (2011) Breakage of B cell tolerance by antigens on follicular dendritic cells Annals of the Rheumatic Diseases. 70: A57-A57
Kikuchi T, El Shikh MM, El Sayed RM, et al. (2010) Anti-phosphorylcholine-opsonized low-density lipoprotein promotes rapid production of proinflammatory cytokines by dendritic cells and natural killer cells. Journal of Periodontal Research. 45: 720-30
El Shikh ME, El Sayed RM, Sukumar S, et al. (2010) Activation of B cells by antigens on follicular dendritic cells. Trends in Immunology. 31: 205-11
Gibb DR, El Shikh M, Kang DJ, et al. (2010) ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo. The Journal of Experimental Medicine. 207: 623-35
Wu Y, El Shikh ME, El Sayed RM, et al. (2009) IL-6 produced by immune complex-activated follicular dendritic cells promotes germinal center reactions, IgG responses and somatic hypermutation. International Immunology. 21: 745-56
El Shikh ME, El Sayed RM, Szakal AK, et al. (2009) T-independent antibody responses to T-dependent antigens: a novel follicular dendritic cell-dependent activity. Journal of Immunology (Baltimore, Md. : 1950). 182: 3482-91
El Shikh ME, El Sayed RM, Wu Y, et al. (2007) TLR4 on follicular dendritic cells: an activation pathway that promotes accessory activity. Journal of Immunology (Baltimore, Md. : 1950). 179: 4444-50
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