I Glenn Sipes

Affiliations: 
University of Arizona, Tucson, AZ 
Area:
Pharmacology, Cell Biology, Biochemistry
Website:
https://pharmacology.arizona.edu/person/i-glenn-sipes-phd
Google:
"Glenn Sipes"
Bio:

http://fragrancesafetypanel.org/wp-content/uploads/2016/09/Sipes.pdf

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Parents

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Joseph Paul Buckley grad student 1969 University of Pittsburgh
 (Studies on the pharmacology and peripheral mechanism of action of fenfluramine hydrochloride)
Bernard Beryl Brodie post-doc 1969-1971 NIH
James R. Gillette post-doc 1971-1973 NIH
BETA: Related publications

Publications

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Kong W, Gu P, Knudsen GA, et al. (2013) Comparison of 2,2-bis(bromomethyl)-1,3-propanediol induced genotoxicity in UROtsa cells and primary rat hepatocytes: relevance of metabolism and oxidative stress. Toxicology Letters. 222: 273-9
Api AM, Ritacco G, Sipes IG. (2013) Disposition and excretion of 14C-AHTN (7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene) and 14c-hhcb (1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta-gamma-2-benzopyran) after intravenous administration to Sprague-Dawley rats and domestic pigs. International Journal of Toxicology. 32: 288-95
Kong W, Kuester RK, Gallegos A, et al. (2011) Induction of DNA damage in human urothelial cells by the brominated flame retardant 2,2-bis(bromomethyl)-1,3-propanediol: role of oxidative stress. Toxicology. 290: 271-7
Mark-Kappeler CJ, Sen N, Lukefahr A, et al. (2011) Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biology of Reproduction. 85: 755-62
Cheng Y, Martinez-Guerrero LJ, Wright SH, et al. (2011) Characterization of the inhibitory effects of N-butylpyridinium chloride and structurally related ionic liquids on organic cation transporters 1/2 and human toxic extrusion transporters 1/2-k in vitro and in vivo. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1755-61
Keating AF, Fernandez SM, Mark-Kappeler CJ, et al. (2011) Inhibition of PIK3 signaling pathway members by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biology of Reproduction. 84: 743-51
Mark-Kappeler CJ, Sen N, Keating AF, et al. (2010) Distribution and responsiveness of rat anti-Müllerian hormone during ovarian development and VCD-induced ovotoxicity. Toxicology and Applied Pharmacology. 249: 1-7
Keating AF, Sen N, Sipes IG, et al. (2010) Dual protective role for glutathione S-transferase class pi against VCD-induced ovotoxicity in the rat ovary. Toxicology and Applied Pharmacology. 247: 71-5
Rad G, Hoehle SI, Kuester RK, et al. (2010) In vitro glucuronidation of 2,2-bis(bromomethyl)-1,3-propanediol by microsomes and hepatocytes from rats and humans. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 957-62
Knudsen GA, Cheng Y, Kuester RK, et al. (2009) Effects of dose and route on the disposition and kinetics of 1-butyl-1-methylpyrrolidinium chloride in male F-344 rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 2171-7
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