Bret E. Poat, Ph.D.

Affiliations: 
2010 Biomedical Sciences Tulane University, New Orleans, LA, United States 
Area:
Virology Biology, Molecular Biology, Microbiology Biology
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"Bret Poat"

Parents

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Srikanta Dash grad student 2010 Tulane
 (Engineering the Jak-STAT pathway to overcome Hepatitis C Virus resistance to interferon.)
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Publications

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Chandra PK, Gunduz F, Hazari S, et al. (2014) Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis. Plos One. 9: e108616
Gunduz F, Aboulnasr FM, Chandra PK, et al. (2012) Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture. Virology Journal. 9: 143
Datta S, Hazari S, Chandra PK, et al. (2011) Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1. Virology Journal. 8: 351
Hazari S, Hefler HJ, Chandra PK, et al. (2011) Hepatocellular carcinoma xenograft supports HCV replication: a mouse model for evaluating antivirals. World Journal of Gastroenterology : Wjg. 17: 300-12
Poat B, Hazari S, Chandra PK, et al. (2010) SH2 modified STAT1 induces HLA-I expression and improves IFN-γ signaling in IFN-α resistant HCV replicon cells. Plos One. 5
Poat B, Hazari S, Chandra PK, et al. (2010) Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication. Virology Journal. 7: 265
Chandra PK, Hazari S, Poat B, et al. (2010) Intracytoplasmic stable expression of IgG1 antibody targeting NS3 helicase inhibits replication of highly efficient hepatitis C Virus 2a clone. Virology Journal. 7: 118
Hazari S, Chandra PK, Poat B, et al. (2010) Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway. Virology Journal. 7: 36
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